Neisseria gonorrhoeae strain GC-195

Gram-negativeCocciNon-motileAerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Betaproteobacteria

Order

Neisseriales

Family

Neisseriaceae

Genus

Neisseria

Description

Neisseria gonorrhoeae strain GC-195 is a Gram-negative bacterium characterized by its cocci shape and arrangement typically found in singles and pairs. This strain is strictly aerobic, requiring oxygen for growth, and is mesophilic, with an optimal temperature of 35°C, which aligns with the body temperature of its hosts. It possesses a unique cellular structure consisting of two membranes and has one replicon. Notably, Neisseria gonorrhoeae GC-195 lacks mobility and does not have flagella. The primary habitat of this strain is host-associated, predominantly within Homo sapiens and other Mammalia. It exhibits a free-living biotic relationship, indicating that while it thrives within a host, it can also exist outside of a host organism under certain conditions. N. gonorrhoeae strain GC-195 is known to cause several health issues in humans, including septicemia, gonorrhea, eye infections, conjunctivitis, male urethritis, and disseminated gonococcal infections. The significant health effects associated with this strain highlight its role as a pathogen in human populations. The ability to cause a range of infections, particularly sexually transmitted diseases, underscores the importance of understanding its biology and ecology for public health. Given its wide host range and pathogenic potential, Neisseria gonorrhoeae strain GC-195 serves as an important subject for ongoing research in microbiology and infectious disease prevention.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassBetaproteobacteria
OrderNeisseriales
FamilyNeisseriaceae
GenusNeisseria
SpeciesNeisseria gonorrhoeae
Strainstrain GC-195

Profile

Physiology
Gram staining propertiesNegative
ShapeCocci
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Neisseria gonorrhoeae strain GC-195
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsAerobe
Optimal temperature35
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Mammalia
Cell arrangementSingles - Pairs
SporulationNot Available
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Neisseria gonorrhoeae strain GC-195

Gene Summary

Adenine Count

522374 bp

Thymine Count

522901 bp

Guanine Count

578543 bp

Cytosine Count

568339 bp

Genome Length

2204983 bp

Protein-coding Genes

2294 genes

Non-Coding Genes

93 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
ngobv family restriction endonucleaseEPH36_06605Not AvailableNegative1139889 - 114062028815.9
dna cytosine methyltransferaseEPH36_06610Not AvailableNegative1140636 - 114190747562.7
3-isopropylmalate dehydratase small subunitEPH36_06615Not AvailableNegative1142074 - 114271524209.7
hypothetical proteinEPH36_06620Not AvailableNegative1142777 - 11430318784.36
3-isopropylmalate dehydratase large subunitEPH36_06625Not AvailableNegative1143126 - 114453550505.3
glutamate--cysteine ligaseEPH36_06630Not AvailablePositive1144787 - 114613649662.1
jab domain-containing proteinEPH36_06635Not AvailablePositive1146259 - 114693625110.4
epoxyqueuosine reductase quehEPH36_06640Not AvailablePositive1147009 - 114773427872.0
cap domain-containing proteinEPH36_06645Not AvailablePositive1147886 - 114916647908.5
gtpase hflxEPH36_06650Not AvailablePositive1149172 - 115035042608.0

Displaying genes 1281 – 1290 of 2386 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
GonorrheaCausesPMC11658436
Eye infectionsCausesPMC11658436
ConjunctivitisCausesPMC11658436
SepticemiaCausesPMC11658436
Male urethritisCausesPMC13191610
GonorrheaCausesPMC1538595
Disseminated gonococcal infectionsCausesPMC1538595
GonorrhoeaCausesPMC3943661
GonorrheaCausesPMC9657967
Disseminated infectionsCausesPMC9657967

Displaying health effects 1 – 10 of 14 in total