Neisseria gonorrhoeae strain GC-188

Gram-negativeCocciNon-motileAerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Betaproteobacteria

Order

Neisseriales

Family

Neisseriaceae

Genus

Neisseria

Description

Neisseria gonorrhoeae strain GC-188 is a Gram-negative bacterium characterized by its cocci shape and arrangement in singles or pairs. This strain is an aerobic organism, thriving in oxygen-rich environments, and is classified as mesophilic, with an optimal growth temperature of 35°C. N. gonorrhoeae GC-188 possesses two membranes and contains a single replicon, indicating its genetic organization. Notably, this strain does not exhibit mobility, as it lacks flagella, and is classified as free-living in its biotic relationships. The primary hosts for N. gonorrhoeae include Homo sapiens and other mammals, highlighting its role as a pathogen in human populations. This strain is associated with various health effects, including gonorrhea, septicemia, eye infections such as conjunctivitis, male urethritis, and disseminated gonococcal infections. The pathogenicity of N. gonorrhoeae GC-188 underscores its significant impact on public health, particularly as it causes both localized and systemic infections in humans. Understanding the specific traits of this strain can aid in the development of targeted treatments and preventive measures against the diseases it causes, reinforcing the importance of microbiological research in addressing infectious diseases.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassBetaproteobacteria
OrderNeisseriales
FamilyNeisseriaceae
GenusNeisseria
SpeciesNeisseria gonorrhoeae
Strainstrain GC-188

Profile

Physiology
Gram staining propertiesNegative
ShapeCocci
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Neisseria gonorrhoeae strain GC-188
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsAerobe
Optimal temperature35
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Mammalia
Cell arrangementSingles - Pairs
SporulationNot Available
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Neisseria gonorrhoeae strain GC-188

Gene Summary

Adenine Count

512830 bp

Thymine Count

509460 bp

Guanine Count

555299 bp

Cytosine Count

569516 bp

Genome Length

2154737 bp

Protein-coding Genes

2202 genes

Non-Coding Genes

94 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
leucyl/phenylalanyl-trna--protein transferaseEPH27_02505Not AvailableNegative432966 - 43369126902.2
ferric iron uptake transcriptional regulatorEPH27_02510Not AvailableNegative433761 - 43419516411.5
fur family transcriptional regulatorEPH27_02515Not AvailableNegative434261 - 4344075319.61
outer membrane protein assembly factor bameEPH27_02520Not AvailablePositive434422 - 43479913953.8
4-hydroxy-tetrahydrodipicolinate reductaseEPH27_02525Not AvailablePositive434809 - 43561828270.8
hypothetical proteinEPH27_02530Not AvailableNegative435732 - 43603712160.4
lipid-a-disaccharide synthaseEPH27_02535Not AvailableNegative436258 - 43743043066.9
rlua family pseudouridine synthaseEPH27_02540Not AvailableNegative437581 - 43857336663.9
rne/rng family ribonucleaseEPH27_02550Not AvailablePositive439066 - 441825101700.0
4-hydroxythreonine-4-phosphate dehydrogenase pdxaEPH27_02555Not AvailableNegative442055 - 44304734532.8

Displaying genes 531 – 540 of 2296 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
GonorrheaCausesPMC11658436
Eye infectionsCausesPMC11658436
ConjunctivitisCausesPMC11658436
SepticemiaCausesPMC11658436
Male urethritisCausesPMC13191610
GonorrheaCausesPMC1538595
Disseminated gonococcal infectionsCausesPMC1538595
GonorrhoeaCausesPMC3943661
GonorrheaCausesPMC9657967
Disseminated infectionsCausesPMC9657967

Displaying health effects 1 – 10 of 14 in total