Neisseria gonorrhoeae strain GC-188

Gram-negativeCocciNon-motileAerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Betaproteobacteria

Order

Neisseriales

Family

Neisseriaceae

Genus

Neisseria

Description

Neisseria gonorrhoeae strain GC-188 is a Gram-negative bacterium characterized by its cocci shape and arrangement in singles or pairs. This strain is an aerobic organism, thriving in oxygen-rich environments, and is classified as mesophilic, with an optimal growth temperature of 35°C. N. gonorrhoeae GC-188 possesses two membranes and contains a single replicon, indicating its genetic organization. Notably, this strain does not exhibit mobility, as it lacks flagella, and is classified as free-living in its biotic relationships. The primary hosts for N. gonorrhoeae include Homo sapiens and other mammals, highlighting its role as a pathogen in human populations. This strain is associated with various health effects, including gonorrhea, septicemia, eye infections such as conjunctivitis, male urethritis, and disseminated gonococcal infections. The pathogenicity of N. gonorrhoeae GC-188 underscores its significant impact on public health, particularly as it causes both localized and systemic infections in humans. Understanding the specific traits of this strain can aid in the development of targeted treatments and preventive measures against the diseases it causes, reinforcing the importance of microbiological research in addressing infectious diseases.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassBetaproteobacteria
OrderNeisseriales
FamilyNeisseriaceae
GenusNeisseria
SpeciesNeisseria gonorrhoeae
Strainstrain GC-188

Profile

Physiology
Gram staining propertiesNegative
ShapeCocci
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Neisseria gonorrhoeae strain GC-188
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsAerobe
Optimal temperature35
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Mammalia
Cell arrangementSingles - Pairs
SporulationNot Available
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Neisseria gonorrhoeae strain GC-188

Gene Summary

Adenine Count

512830 bp

Thymine Count

509460 bp

Guanine Count

555299 bp

Cytosine Count

569516 bp

Genome Length

2154737 bp

Protein-coding Genes

2202 genes

Non-Coding Genes

94 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
carboxylating nicotinate-nucleotide diphosphorylaseEPH27_11370Not AvailablePositive1964584 - 196546531192.4
hypothetical proteinEPH27_11375Not AvailableNegative1965766 - 19660329758.21
arsr family transcriptional regulatorEPH27_11380Not AvailablePositive1966089 - 196637010564.1
exodeoxyribonuclease iiiEPH27_11385Not AvailablePositive1966430 - 196720029169.9
hypothetical proteinEPH27_11390Not AvailableNegative1967240 - 19673865089.05
glycine zipper 2tm domain-containing proteinEPH27_11395Not AvailableNegative1967474 - 196815123472.8
hypothetical proteinEPH27_11410Not AvailableNegative1968965 - 196926111410.6
tigr01666 family membrane proteinEPH27_11415Not AvailableNegative1969673 - 197182379823.5
pilt/pilu family type 4a pilus atpaseEPH27_11420Not AvailableNegative1971940 - 197316645671.1
type iv pilus twitching motility protein piltEPH27_11425Not AvailableNegative1973330 - 197437337942.6

Displaying genes 2061 – 2070 of 2296 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
GonorrheaCausesPMC11658436
Eye infectionsCausesPMC11658436
ConjunctivitisCausesPMC11658436
SepticemiaCausesPMC11658436
Male urethritisCausesPMC13191610
GonorrheaCausesPMC1538595
Disseminated gonococcal infectionsCausesPMC1538595
GonorrhoeaCausesPMC3943661
GonorrheaCausesPMC9657967
Disseminated infectionsCausesPMC9657967

Displaying health effects 1 – 10 of 14 in total