Neisseria gonorrhoeae strain GC-186

Gram-negativeCocciNon-motileAerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Betaproteobacteria

Order

Neisseriales

Family

Neisseriaceae

Genus

Neisseria

Description

Neisseria gonorrhoeae strain GC-186 is a Gram-negative bacterium characterized by its cocci shape and arrangement in singles and pairs. This strain is an aerobic organism, thriving in oxygen-rich environments, with an optimal growth temperature of 35°C, placing it within the mesophilic temperature range. It possesses two membranes and is devoid of flagella, indicating a non-motile lifestyle. GC-186 is associated with hosts, particularly Homo sapiens and other mammals, and is recognized for its pathogenic relationships, causing a range of health issues. These include septicemia, gonorrhea, eye infections, conjunctivitis, male urethritis, and disseminated gonococcal infections, indicating its significant impact on human health. Despite its pathogenic capabilities, N. gonorrhoeae strain GC-186 also exhibits a free-living biotic relationship, which may facilitate its survival and transmission in host populations. The presence of a single replicon suggests a streamlined genomic organization, potentially contributing to its adaptability within various biological niches. Understanding the characteristics of N. gonorrhoeae strain GC-186 can provide insights into its ecological role and transmission dynamics, particularly in human populations where it contributes to significant health concerns. By studying its habitat association and pathogenic effects, researchers can develop targeted interventions to manage and prevent infections caused by this strain.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassBetaproteobacteria
OrderNeisseriales
FamilyNeisseriaceae
GenusNeisseria
SpeciesNeisseria gonorrhoeae
Strainstrain GC-186

Profile

Physiology
Gram staining propertiesNegative
ShapeCocci
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Neisseria gonorrhoeae strain GC-186
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsAerobe
Optimal temperature35
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Mammalia
Cell arrangementSingles - Pairs
SporulationNot Available
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Neisseria gonorrhoeae strain GC-186

Gene Summary

Adenine Count

509815 bp

Thymine Count

516233 bp

Guanine Count

565420 bp

Cytosine Count

563069 bp

Genome Length

2162646 bp

Protein-coding Genes

2231 genes

Non-Coding Genes

94 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
ribosomal rna small subunit methyltransferase jEPH26_11380Not AvailableNegative1964600 - 196535227331.8
sigma-54-dependent fis family transcriptional regulatorEPH26_11385Not AvailableNegative1965452 - 196717665065.5
dna topoisomerase iv subunit aEPH26_11390Not AvailableNegative1967196 - 196949984497.6
2,3-diphosphoglycerate-dependent phosphoglycerate mutaseEPH26_11395Not AvailablePositive1969648 - 197033125930.0
hypothetical proteinEPH26_11400Not AvailablePositive1970348 - 19704915375.44
tigr01666 family membrane proteinEPH26_11410Not AvailableNegative1971879 - 197402979823.5
pilt/pilu family type 4a pilus atpaseEPH26_11415Not AvailableNegative1974146 - 197537245671.1
type iv pilus twitching motility protein piltEPH26_11420Not AvailableNegative1975536 - 197657937942.6
yggs family pyridoxal phosphate-dependent enzymeEPH26_11425Not AvailablePositive1976699 - 197738524985.2
rna-binding proteinEPH26_11430Not AvailablePositive1977385 - 197779215518.4

Displaying genes 2071 – 2080 of 2325 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
GonorrheaCausesPMC11658436
Eye infectionsCausesPMC11658436
ConjunctivitisCausesPMC11658436
SepticemiaCausesPMC11658436
Male urethritisCausesPMC13191610
GonorrheaCausesPMC1538595
Disseminated gonococcal infectionsCausesPMC1538595
GonorrhoeaCausesPMC3943661
GonorrheaCausesPMC9657967
Disseminated infectionsCausesPMC9657967

Displaying health effects 1 – 10 of 14 in total