Neisseria gonorrhoeae strain GC-186

Gram-negativeCocciNon-motileAerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Betaproteobacteria

Order

Neisseriales

Family

Neisseriaceae

Genus

Neisseria

Description

Neisseria gonorrhoeae strain GC-186 is a Gram-negative bacterium characterized by its cocci shape and arrangement in singles and pairs. This strain is an aerobic organism, thriving in oxygen-rich environments, with an optimal growth temperature of 35°C, placing it within the mesophilic temperature range. It possesses two membranes and is devoid of flagella, indicating a non-motile lifestyle. GC-186 is associated with hosts, particularly Homo sapiens and other mammals, and is recognized for its pathogenic relationships, causing a range of health issues. These include septicemia, gonorrhea, eye infections, conjunctivitis, male urethritis, and disseminated gonococcal infections, indicating its significant impact on human health. Despite its pathogenic capabilities, N. gonorrhoeae strain GC-186 also exhibits a free-living biotic relationship, which may facilitate its survival and transmission in host populations. The presence of a single replicon suggests a streamlined genomic organization, potentially contributing to its adaptability within various biological niches. Understanding the characteristics of N. gonorrhoeae strain GC-186 can provide insights into its ecological role and transmission dynamics, particularly in human populations where it contributes to significant health concerns. By studying its habitat association and pathogenic effects, researchers can develop targeted interventions to manage and prevent infections caused by this strain.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassBetaproteobacteria
OrderNeisseriales
FamilyNeisseriaceae
GenusNeisseria
SpeciesNeisseria gonorrhoeae
Strainstrain GC-186

Profile

Physiology
Gram staining propertiesNegative
ShapeCocci
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Neisseria gonorrhoeae strain GC-186
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsAerobe
Optimal temperature35
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Mammalia
Cell arrangementSingles - Pairs
SporulationNot Available
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Neisseria gonorrhoeae strain GC-186

Gene Summary

Adenine Count

509815 bp

Thymine Count

516233 bp

Guanine Count

565420 bp

Cytosine Count

563069 bp

Genome Length

2162646 bp

Protein-coding Genes

2231 genes

Non-Coding Genes

94 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
is630 family transposaseEPH26_10365Not AvailableNegative1788299 - 178869214657.9
dna-protecting protein dpraEPH26_10370Not AvailableNegative1788703 - 178989041883.4
sigma-54-dependent fis family transcriptional regulatorEPH26_10375Not AvailableNegative1789981 - 179125846521.7
hamp domain-containing histidine kinaseEPH26_10380Not AvailableNegative1791251 - 179337176725.6
duf4390 domain-containing proteinEPH26_10385Not AvailableNegative1793371 - 179397021931.4
16s rrna (cytosine(967)-c(5))-methyltransferase rsmbEPH26_10390Not AvailableNegative1793936 - 179519546372.6
methionyl-trna formyltransferaseEPH26_10395Not AvailableNegative1795274 - 179620032814.7
peptide deformylaseEPH26_10400Not AvailableNegative1796288 - 179683320994.7
lysm peptidoglycan-binding domain-containing proteinEPH26_10410Not AvailablePositive1797089 - 179842650071.9
aspartate carbamoyltransferase regulatory subunitEPH26_10425Not AvailableNegative1799558 - 180001616916.4

Displaying genes 1891 – 1900 of 2325 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
GonorrheaCausesPMC11658436
Eye infectionsCausesPMC11658436
ConjunctivitisCausesPMC11658436
SepticemiaCausesPMC11658436
Male urethritisCausesPMC13191610
GonorrheaCausesPMC1538595
Disseminated gonococcal infectionsCausesPMC1538595
GonorrhoeaCausesPMC3943661
GonorrheaCausesPMC9657967
Disseminated infectionsCausesPMC9657967

Displaying health effects 1 – 10 of 14 in total