Neisseria gonorrhoeae strain GC-186

Gram-negativeCocciNon-motileAerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Betaproteobacteria

Order

Neisseriales

Family

Neisseriaceae

Genus

Neisseria

Description

Neisseria gonorrhoeae strain GC-186 is a Gram-negative bacterium characterized by its cocci shape and arrangement in singles and pairs. This strain is an aerobic organism, thriving in oxygen-rich environments, with an optimal growth temperature of 35°C, placing it within the mesophilic temperature range. It possesses two membranes and is devoid of flagella, indicating a non-motile lifestyle. GC-186 is associated with hosts, particularly Homo sapiens and other mammals, and is recognized for its pathogenic relationships, causing a range of health issues. These include septicemia, gonorrhea, eye infections, conjunctivitis, male urethritis, and disseminated gonococcal infections, indicating its significant impact on human health. Despite its pathogenic capabilities, N. gonorrhoeae strain GC-186 also exhibits a free-living biotic relationship, which may facilitate its survival and transmission in host populations. The presence of a single replicon suggests a streamlined genomic organization, potentially contributing to its adaptability within various biological niches. Understanding the characteristics of N. gonorrhoeae strain GC-186 can provide insights into its ecological role and transmission dynamics, particularly in human populations where it contributes to significant health concerns. By studying its habitat association and pathogenic effects, researchers can develop targeted interventions to manage and prevent infections caused by this strain.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassBetaproteobacteria
OrderNeisseriales
FamilyNeisseriaceae
GenusNeisseria
SpeciesNeisseria gonorrhoeae
Strainstrain GC-186

Profile

Physiology
Gram staining propertiesNegative
ShapeCocci
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Neisseria gonorrhoeae strain GC-186
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsAerobe
Optimal temperature35
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Mammalia
Cell arrangementSingles - Pairs
SporulationNot Available
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Neisseria gonorrhoeae strain GC-186

Gene Summary

Adenine Count

509815 bp

Thymine Count

516233 bp

Guanine Count

565420 bp

Cytosine Count

563069 bp

Genome Length

2162646 bp

Protein-coding Genes

2231 genes

Non-Coding Genes

94 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
2-oxoglutarate dehydrogenase complex dihydrolipoyllysine-residue succinyltransferaseEPH26_07995Not AvailablePositive1381148 - 138232941687.6
dihydrolipoyl dehydrogenaseEPH26_08000Not AvailablePositive1382590 - 138402350110.2
hypothetical proteinEPH26_08005Not AvailablePositive1384143 - 138443010974.1
adp-forming succinate--coa ligase subunit betaEPH26_08010Not AvailablePositive1384502 - 138566841295.9
succinate--coa ligase subunit alphaEPH26_08015Not AvailablePositive1385679 - 138656930565.1
hypothetical proteinEPH26_08030Not AvailablePositive1387452 - 138780913281.3
duf2786 domain-containing proteinEPH26_08035Not AvailablePositive1387820 - 138850325648.9
hypothetical proteinEPH26_08040Not AvailablePositive1388698 - 13889679656.73
hypothetical proteinEPH26_08050Not AvailableNegative1389323 - 138967913582.2
Trna-serNot AvailableNot AvailablePositive1390714 - 1390803Not Available

Displaying genes 1511 – 1520 of 2325 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
GonorrheaCausesPMC11658436
Eye infectionsCausesPMC11658436
ConjunctivitisCausesPMC11658436
SepticemiaCausesPMC11658436
Male urethritisCausesPMC13191610
GonorrheaCausesPMC1538595
Disseminated gonococcal infectionsCausesPMC1538595
GonorrhoeaCausesPMC3943661
GonorrheaCausesPMC9657967
Disseminated infectionsCausesPMC9657967

Displaying health effects 1 – 10 of 14 in total