Neisseria gonorrhoeae strain GC-185

Gram-negativeCocciNon-motileAerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Betaproteobacteria

Order

Neisseriales

Family

Neisseriaceae

Genus

Neisseria

Description

Neisseria gonorrhoeae strain GC-185 is a Gram-negative cocci bacterium primarily associated with human hosts (Homo sapiens) and other mammals (Mammalia). This strain exhibits a single-pair cell arrangement and is classified as an aerobe, indicating its requirement for oxygen for growth and survival. It is non-motile, lacking flagella, which suggests that it relies on other mechanisms for dispersal and infection. The optimal growth temperature for N. gonorrhoeae GC-185 is 35°C, and it thrives within a mesophilic temperature range. The bacterium possesses two membranes and has a single replicon, characteristic of its cellular structure. Its biotic relationship is categorized as free-living, although it primarily exists in a host-associated habitat. N. gonorrhoeae is notable for its health effects, contributing to a range of medical conditions, including gonorrhea, conjunctivitis, male urethritis, and septicemia. Disseminated gonococcal infections are also associated with this strain, highlighting its potential to cause widespread infections in the host. The ecological insight into N. gonorrhoeae GC-185 emphasizes its role as a pathogen in human health, particularly in sexually transmitted infections. Its ability to thrive in host-associated environments and its pathogenicity underscore the importance of monitoring and controlling its spread to mitigate public health risks. The strain's characteristics and effects on health further highlight the need for ongoing research and awareness to address infections caused by this organism.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassBetaproteobacteria
OrderNeisseriales
FamilyNeisseriaceae
GenusNeisseria
SpeciesNeisseria gonorrhoeae
Strainstrain GC-185

Profile

Physiology
Gram staining propertiesNegative
ShapeCocci
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Neisseria gonorrhoeae strain GC-185
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsAerobe
Optimal temperature35
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Mammalia
Cell arrangementSingles - Pairs
SporulationNot Available
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Neisseria gonorrhoeae strain GC-185

Gene Summary

Adenine Count

513851 bp

Thymine Count

509061 bp

Guanine Count

555589 bp

Cytosine Count

570689 bp

Genome Length

2157140 bp

Protein-coding Genes

2215 genes

Non-Coding Genes

92 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
nitric-oxide reductase large subunitEPH31_11355Not AvailableNegative1966349 - 196860484348.4
nitrite reductase, copper-containingEPH31_11360Not AvailablePositive1968978 - 197015640909.4
formylglycine-generating enzyme family proteinEPH31_11365Not AvailablePositive1970334 - 197108927865.9
pilinEPH31_11370Not AvailablePositive1971326 - 197173614623.0
hypothetical proteinEPH31_11375Not AvailablePositive1972012 - 19722669482.57
hypothetical proteinEPH31_11380Not AvailablePositive1972404 - 19726047174.5
ribosomal rna small subunit methyltransferase jEPH31_11385Not AvailableNegative1972782 - 197353427331.8
sigma-54-dependent fis family transcriptional regulatorEPH31_11390Not AvailableNegative1973634 - 197535865065.5
dna topoisomerase iv subunit aEPH31_11395Not AvailableNegative1975378 - 197768184497.6
2,3-diphosphoglycerate-dependent phosphoglycerate mutaseEPH31_11400Not AvailablePositive1977830 - 197851325930.0

Displaying genes 2061 – 2070 of 2307 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
GonorrheaCausesPMC11658436
Eye infectionsCausesPMC11658436
ConjunctivitisCausesPMC11658436
SepticemiaCausesPMC11658436
Male urethritisCausesPMC13191610
GonorrheaCausesPMC1538595
Disseminated gonococcal infectionsCausesPMC1538595
GonorrhoeaCausesPMC3943661
GonorrheaCausesPMC9657967
Disseminated infectionsCausesPMC9657967

Displaying health effects 1 – 10 of 14 in total