Neisseria gonorrhoeae strain gc-167

Gram-negativeCocciNon-motileAerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Betaproteobacteria

Order

Neisseriales

Family

Neisseriaceae

Genus

Neisseria

Description

Neisseria gonorrhoeae strain gc-167 is a Gram-negative bacterium characterized by its cocci shape and arrangement in singles and pairs. It is an aerobic organism, requiring oxygen for growth, and is classified as mesophilic, with an optimal temperature of 35°C. This strain possesses two membranes and a single replicon, indicating its cellular structure and genetic organization. N. gonorrhoeae strain gc-167 is notable for its pathogenicity in humans, primarily causing infections such as gonorrhea, septicemia, male urethritis, and eye infections, including conjunctivitis. Additionally, it can lead to disseminated gonococcal infections, highlighting its potential to spread beyond the initial site of infection. The bacterium is free-living but primarily associated with hosts, specifically Homo sapiens and other mammals. This strain's inability to move, as it lacks flagella, suggests that its transmission relies on direct contact during sexual activity or from mother to child during childbirth, particularly in the case of eye infections. The implications of its pathogenicity are significant for public health, as N. gonorrhoeae is known for its increasing antibiotic resistance, making infections difficult to treat. The ecological insight provided by this strain underscores the importance of understanding its behavior within host-associated environments and the need for ongoing surveillance and research to address the challenges posed by its infections.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassBetaproteobacteria
OrderNeisseriales
FamilyNeisseriaceae
GenusNeisseria
SpeciesNeisseria gonorrhoeae
Strainstrain gc-167

Profile

Physiology
Gram staining propertiesNegative
ShapeCocci
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Neisseria gonorrhoeae strain gc-167
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsAerobe
Optimal temperature35
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Mammalia
Cell arrangementSingles - Pairs
SporulationNot Available
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Neisseria gonorrhoeae strain gc-167


Gene Summary

Adenine Count

495691 bp

Thymine Count

499966 bp

Guanine Count

553873 bp

Cytosine Count

551785 bp

Genome Length

2109106 bp

Protein-coding Genes

2176 genes

Non-Coding Genes

82 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
hypoxanthine-guanine phosphoribosyltransferaseEPH10_03235Not AvailablePositive546130 - 54669320870.3
pts sugar transporter subunit iiaEPH10_03240Not AvailablePositive546776 - 54721315662.9
hpr family phosphocarrier proteinEPH10_03245Not AvailablePositive547434 - 5477039622.65
phosphoenolpyruvate--protein phosphotransferaseEPH10_03250Not AvailablePositive547703 - 54947864983.4
abc transporter atp-binding proteinEPH10_03255Not AvailableNegative549605 - 55054634110.7
nudix domain-containing proteinEPH10_03260Not AvailableNegative550555 - 55143032351.4
hypothetical proteinEPH10_03265Not AvailableNegative551384 - 5516118442.34
Trna-metNot AvailableNot AvailablePositive551613 - 551689Not Available
phosphomethylpyrimidine synthase thicEPH10_03275Not AvailablePositive552028 - 55392971286.9
glycosyltransferase family 25 proteinEPH10_03285Not AvailablePositive555242 - 55608131796.2

Displaying genes 651 – 660 of 2258 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
GonorrheaCausesPMC11658436
Eye infectionsCausesPMC11658436
ConjunctivitisCausesPMC11658436
SepticemiaCausesPMC11658436
Male urethritisCausesPMC13191610
GonorrheaCausesPMC1538595
Disseminated gonococcal infectionsCausesPMC1538595
GonorrhoeaCausesPMC3943661
GonorrheaCausesPMC9657967
Disseminated infectionsCausesPMC9657967

Displaying health effects 1 – 10 of 14 in total