Neisseria gonorrhoeae strain gc-167

Gram-negativeCocciNon-motileAerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Betaproteobacteria

Order

Neisseriales

Family

Neisseriaceae

Genus

Neisseria

Description

Neisseria gonorrhoeae strain gc-167 is a Gram-negative bacterium characterized by its cocci shape and arrangement in singles and pairs. It is an aerobic organism, requiring oxygen for growth, and is classified as mesophilic, with an optimal temperature of 35°C. This strain possesses two membranes and a single replicon, indicating its cellular structure and genetic organization. N. gonorrhoeae strain gc-167 is notable for its pathogenicity in humans, primarily causing infections such as gonorrhea, septicemia, male urethritis, and eye infections, including conjunctivitis. Additionally, it can lead to disseminated gonococcal infections, highlighting its potential to spread beyond the initial site of infection. The bacterium is free-living but primarily associated with hosts, specifically Homo sapiens and other mammals. This strain's inability to move, as it lacks flagella, suggests that its transmission relies on direct contact during sexual activity or from mother to child during childbirth, particularly in the case of eye infections. The implications of its pathogenicity are significant for public health, as N. gonorrhoeae is known for its increasing antibiotic resistance, making infections difficult to treat. The ecological insight provided by this strain underscores the importance of understanding its behavior within host-associated environments and the need for ongoing surveillance and research to address the challenges posed by its infections.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassBetaproteobacteria
OrderNeisseriales
FamilyNeisseriaceae
GenusNeisseria
SpeciesNeisseria gonorrhoeae
Strainstrain gc-167

Profile

Physiology
Gram staining propertiesNegative
ShapeCocci
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Neisseria gonorrhoeae strain gc-167
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsAerobe
Optimal temperature35
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Mammalia
Cell arrangementSingles - Pairs
SporulationNot Available
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Neisseria gonorrhoeae strain gc-167

Gene Summary

Adenine Count

495691 bp

Thymine Count

499966 bp

Guanine Count

553873 bp

Cytosine Count

551785 bp

Genome Length

2109106 bp

Protein-coding Genes

2176 genes

Non-Coding Genes

82 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
hypothetical proteinEPH10_07235Not AvailableNegative1252080 - 125246313464.4
re/si-specific nad(p)(+) transhydrogenase subunit alphaEPH10_07240Not AvailableNegative1252467 - 125400553619.6
hypothetical proteinEPH10_07245Not AvailableNegative1254120 - 12542484908.1
phosphoserine phosphatase serbEPH10_07250Not AvailablePositive1254294 - 125512730587.0
chloride channel proteinEPH10_07255Not AvailablePositive1255272 - 125641440030.9
bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/imp cyclohydrolaseEPH10_07260Not AvailablePositive1256575 - 125815556632.4
opacity protein opa54EPH10_07270Not AvailablePositive1258978 - 125935314330.7
is1595 family transposaseEPH10_07275Not AvailablePositive1259354 - 12595296774.24
3-isopropylmalate dehydrogenaseEPH10_07280Not AvailableNegative1259557 - 126062739027.6
ngobv family restriction endonucleaseEPH10_07285Not AvailableNegative1260661 - 126139228815.9

Displaying genes 1371 – 1380 of 2258 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
GonorrheaCausesPMC11658436
Eye infectionsCausesPMC11658436
ConjunctivitisCausesPMC11658436
SepticemiaCausesPMC11658436
Male urethritisCausesPMC13191610
GonorrheaCausesPMC1538595
Disseminated gonococcal infectionsCausesPMC1538595
GonorrhoeaCausesPMC3943661
GonorrheaCausesPMC9657967
Disseminated infectionsCausesPMC9657967

Displaying health effects 1 – 10 of 14 in total