Neisseria gonorrhoeae strain gc-167

Gram-negativeCocciNon-motileAerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Betaproteobacteria

Order

Neisseriales

Family

Neisseriaceae

Genus

Neisseria

Description

Neisseria gonorrhoeae strain gc-167 is a Gram-negative bacterium characterized by its cocci shape and arrangement in singles and pairs. It is an aerobic organism, requiring oxygen for growth, and is classified as mesophilic, with an optimal temperature of 35°C. This strain possesses two membranes and a single replicon, indicating its cellular structure and genetic organization. N. gonorrhoeae strain gc-167 is notable for its pathogenicity in humans, primarily causing infections such as gonorrhea, septicemia, male urethritis, and eye infections, including conjunctivitis. Additionally, it can lead to disseminated gonococcal infections, highlighting its potential to spread beyond the initial site of infection. The bacterium is free-living but primarily associated with hosts, specifically Homo sapiens and other mammals. This strain's inability to move, as it lacks flagella, suggests that its transmission relies on direct contact during sexual activity or from mother to child during childbirth, particularly in the case of eye infections. The implications of its pathogenicity are significant for public health, as N. gonorrhoeae is known for its increasing antibiotic resistance, making infections difficult to treat. The ecological insight provided by this strain underscores the importance of understanding its behavior within host-associated environments and the need for ongoing surveillance and research to address the challenges posed by its infections.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassBetaproteobacteria
OrderNeisseriales
FamilyNeisseriaceae
GenusNeisseria
SpeciesNeisseria gonorrhoeae
Strainstrain gc-167

Profile

Physiology
Gram staining propertiesNegative
ShapeCocci
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Neisseria gonorrhoeae strain gc-167
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsAerobe
Optimal temperature35
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Mammalia
Cell arrangementSingles - Pairs
SporulationNot Available
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Neisseria gonorrhoeae strain gc-167

Gene Summary

Adenine Count

495691 bp

Thymine Count

499966 bp

Guanine Count

553873 bp

Cytosine Count

551785 bp

Genome Length

2109106 bp

Protein-coding Genes

2176 genes

Non-Coding Genes

82 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
is1595 family transposaseEPH10_05970Not AvailablePositive1016680 - 10167763741.59
dna gyrase subunit aEPH10_05975Not AvailableNegative1016995 - 1019745101409.0
fe-s protein assembly co-chaperone hscbEPH10_05980Not AvailableNegative1019843 - 102034318994.4
alternative ribosome-rescue factor aEPH10_05985Not AvailablePositive1020425 - 10206468452.33
iron-sulfur cluster assembly protein iscaEPH10_05990Not AvailableNegative1020606 - 102092611638.7
fe-s cluster assembly scaffold iscuEPH10_05995Not AvailableNegative1021013 - 102139913919.5
cell filamentation protein ficEPH10_06000Not AvailableNegative1021412 - 102190619447.5
hypothetical proteinEPH10_06005Not AvailableNegative1022212 - 102250211387.9
iscs subfamily cysteine desulfuraseEPH10_06010Not AvailableNegative1022508 - 102372244580.5
fe-s cluster assembly transcriptional regulator iscrEPH10_06015Not AvailableNegative1023751 - 102419716000.2

Displaying genes 1141 – 1150 of 2258 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
GonorrheaCausesPMC11658436
Eye infectionsCausesPMC11658436
ConjunctivitisCausesPMC11658436
SepticemiaCausesPMC11658436
Male urethritisCausesPMC13191610
GonorrheaCausesPMC1538595
Disseminated gonococcal infectionsCausesPMC1538595
GonorrhoeaCausesPMC3943661
GonorrheaCausesPMC9657967
Disseminated infectionsCausesPMC9657967

Displaying health effects 1 – 10 of 14 in total