Klebsiella pneumoniae subsp. pneumoniae strain R1786

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae subsp. pneumoniae strain R1786 is a Gram-negative, rod-shaped bacterium associated with hosts. This strain exhibits a unique cell arrangement, often found in chains, pairs, and singles. It is a facultative anaerobe, capable of thriving in both aerobic and anaerobic environments, and it shows mobility due to the presence of flagella. The optimal growth temperature for this strain is 37°C, placing it within the mesophilic range, which is conducive to growth in mammalian hosts. As a chemoheterotroph, K. pneumoniae subsp. pneumoniae R1786 derives its energy from organic compounds, reflecting its adaptation to a host-associated habitat. This strain is free-living, indicating its ability to survive independently while also being implicated in significant health effects, particularly pneumonia and community-acquired pneumonia (CAP). Its nonsporulating nature suggests that it does not form spores to resist adverse conditions, which may limit its survival outside of host environments. With one replicon and two membranes, the strain's genetic and cellular structure supports its pathogenicity and adaptability. The health implications of K. pneumoniae subsp. pneumoniae R1786 highlight the importance of understanding bacterial behavior in clinical contexts, particularly in relation to respiratory infections. The observation that this strain is associated with community-acquired infections underscores its ecological role in human health, emphasizing the relevance of monitoring such bacteria in public health initiatives.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainsubsp. pneumoniae strain R1786

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae subsp. pneumoniae strain R1786
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityNot Available

Genome Summary

Klebsiella pneumoniae subsp. pneumoniae strain R1786

Gene Summary

Adenine Count

1307973 bp

Thymine Count

1302590 bp

Guanine Count

1696365 bp

Cytosine Count

1707835 bp

Genome Length

6027117 bp

Protein-coding Genes

5699 genes

Non-Coding Genes

305 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
cupin domain-containing proteinEJ893_01300Not AvailableNegative232849 - 23397042650.1
two-component system sensor histidine kinase phoqEJ893_01305Not AvailableNegative234056 - 23552255507.0
two-component system response regulator phopEJ893_01310Not AvailableNegative235522 - 23619325432.6
arac family transcriptional regulatorEJ893_01315Not AvailablePositive236477 - 23728330365.1
cupin domain-containing proteinEJ893_01320Not AvailablePositive237367 - 23772913664.5
adenylosuccinate lyaseEJ893_01325Not AvailableNegative237784 - 23915451660.8
lysogenization regulator hfldEJ893_01330Not AvailableNegative239158 - 23979922937.0
trna 2-thiouridine(34) synthase mnmaEJ893_01335Not AvailableNegative239854 - 24096041018.8
nudix hydrolaseEJ893_01340Not AvailableNegative241017 - 24147517302.6
23s rrna pseudouridine(2457) synthase rlueEJ893_01345Not AvailableNegative241492 - 24214224699.8

Displaying genes 571 – 580 of 6015 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
PneumoniaCausesPMC475056
Community-acquired pneumonia (cap)CausesPMC7609860

Displaying health effects 1 – 2 of 2 in total