Klebsiella pneumoniae subsp. pneumoniae strain R1786

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae subsp. pneumoniae strain R1786 is a Gram-negative, rod-shaped bacterium associated with hosts. This strain exhibits a unique cell arrangement, often found in chains, pairs, and singles. It is a facultative anaerobe, capable of thriving in both aerobic and anaerobic environments, and it shows mobility due to the presence of flagella. The optimal growth temperature for this strain is 37°C, placing it within the mesophilic range, which is conducive to growth in mammalian hosts. As a chemoheterotroph, K. pneumoniae subsp. pneumoniae R1786 derives its energy from organic compounds, reflecting its adaptation to a host-associated habitat. This strain is free-living, indicating its ability to survive independently while also being implicated in significant health effects, particularly pneumonia and community-acquired pneumonia (CAP). Its nonsporulating nature suggests that it does not form spores to resist adverse conditions, which may limit its survival outside of host environments. With one replicon and two membranes, the strain's genetic and cellular structure supports its pathogenicity and adaptability. The health implications of K. pneumoniae subsp. pneumoniae R1786 highlight the importance of understanding bacterial behavior in clinical contexts, particularly in relation to respiratory infections. The observation that this strain is associated with community-acquired infections underscores its ecological role in human health, emphasizing the relevance of monitoring such bacteria in public health initiatives.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainsubsp. pneumoniae strain R1786

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae subsp. pneumoniae strain R1786
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityNot Available

Genome Summary

Klebsiella pneumoniae subsp. pneumoniae strain R1786

Gene Summary

Adenine Count

1307973 bp

Thymine Count

1302590 bp

Guanine Count

1696365 bp

Cytosine Count

1707835 bp

Genome Length

6027117 bp

Protein-coding Genes

5699 genes

Non-Coding Genes

305 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
n-acetyltransferaseEJ893_17730Not AvailablePositive3386168 - 338670420887.4
hypothetical proteinEJ893_17735Not AvailableNegative3386833 - 338747424381.8
diacetyl reductase ((s)-acetoin forming)EJ893_17740Not AvailableNegative3387868 - 338863826644.0
acetolactate synthase alssEJ893_17745Not AvailableNegative3388662 - 339034160294.4
acetolactate decarboxylaseEJ893_17750Not AvailableNegative3390351 - 339113029223.4
lysr family transcriptional regulatorEJ893_17755Not AvailablePositive3391237 - 339210932555.4
3-hydroxybutyrate dehydrogenaseEJ893_17760Not AvailableNegative3392129 - 339289927029.5
gntp family permeaseEJ893_17765Not AvailableNegative3392923 - 339431448436.6
3-hydroxyacyl-coa dehydrogenase family proteinEJ893_17770Not AvailableNegative3394362 - 339528533137.3
coa transferase subunit bEJ893_17780Not AvailableNegative3396488 - 339714423147.4

Displaying genes 3611 – 3620 of 6015 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
PneumoniaCausesPMC475056
Community-acquired pneumonia (cap)CausesPMC7609860

Displaying health effects 1 – 2 of 2 in total