Escherichia coli strain PNUSAE018855

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Escherichia

Description

Escherichia coli strain PNUSAE018855 is a Gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic metabolism, allowing it to thrive in diverse environments, including both aerobic and anaerobic conditions. This strain typically exists in pairs or singles and possesses flagella, enabling mobility. The optimal growth temperature for E. coli PNUSAE018855 is 37°C, classifying it as mesophilic, with a temperature range that supports its growth in various host-associated habitats. This strain is biotically associated with a wide array of hosts, including Homo sapiens (humans), Gallus gallus (chickens), Bos taurus (cattle), and several other mammals, birds, and even plants like Solanum lycopersicum (tomato) and Brassica oleracea var. italica (broccoli). Such a diverse host range indicates its adaptability and potential ecological significance. E. coli PNUSAE018855 is notable for its pathogenicity in humans, being linked to numerous health effects including urinary tract infections (UTIs), gastrointestinal infections, and severe conditions such as neonatal meningitis and hemolytic uremic syndrome (HUS). The strain's ability to cause a wide range of illnesses underscores its importance in clinical microbiology and public health. Given its role in both free-living and host-associated contexts, E. coli PNUSAE018855 exemplifies the complex interactions between pathogens and their hosts, highlighting the necessity for continuous monitoring and research to understand its impact on health and disease dynamics.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusEscherichia
SpeciesEscherichia coli
Strainstrain PNUSAE018855

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Escherichia coli strain PNUSAE018855
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Bos taurus
Cell arrangementPairs - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Escherichia coli strain PNUSAE018855

Gene Summary

Adenine Count

1262343 bp

Thymine Count

1247779 bp

Guanine Count

1277540 bp

Cytosine Count

1294110 bp

Genome Length

5094894 bp

Protein-coding Genes

4632 genes

Non-Coding Genes

367 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
bifunctional murein dd-endopeptidase/murein ld-carboxypeptidaseD7Y10_RS03975Not AvailablePositive854391 - 85495721041.1
cyclic di-gmp phosphodiesteraseD7Y10_RS03980Not AvailablePositive855138 - 85668858275.2
abc transporter substrate-binding proteinD7Y10_RS03985Not AvailablePositive856776 - 85859069772.7
microcin c abc transporter permease yejbD7Y10_RS03990Not AvailablePositive858591 - 85968540362.6
abc transporter permeaseD7Y10_RS03995Not AvailablePositive859685 - 86071038108.7
microcin c abc transporter atp-binding protein yejfD7Y10_RS04000Not AvailablePositive860712 - 86230158670.7
hypothetical proteinD7Y10_RS04005Not AvailableNegative862305 - 86264912525.9
multidrug efflux mfs transporter bcrD7Y10_RS04010Not AvailableNegative862983 - 86417343369.4
16s rrna pseudouridine(516) synthase rsuaD7Y10_RS04015Not AvailableNegative864201 - 86489625880.8
dead/deah box helicaseD7Y10_RS04020Not AvailablePositive865046 - 86680666476.9

Displaying genes 1101 – 1110 of 4999 in total

Metabolites

4785 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000173(R)-3-Hydroxybutyric acidC4H8O3Chemical structure of (R)-3-Hydroxybutyric acid625-72-3
Average104.0473Da
Monoisotopic104.047344122Da
BASm0000217alpha-ribazoleC14H18N2O4Chemical structure of alpha-ribazoleNot available
Average278.3037Da
Monoisotopic278.126657074Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm0000238(R)-3-phenyllactateC9H9O3Chemical structure of (R)-3-phenyllactateNot available
Average165.169Da
Monoisotopic165.05571773Da
BASm00002482,3-dihydroxy-3-methylbutanoateC5H10O4Chemical structure of 2,3-dihydroxy-3-methylbutanoate1756-18-9
Average134.1305Da
Monoisotopic134.0579088Da
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm00002593alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da
BASm00002603alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da

Displaying 1–10 of 4785 metabolites

Health Effects

Health ConditionRelationReference
Gi diseaseCausesPMC11149725
UtisCausesPMC11434687
Colorectal cancerCausesPMC12198655
Pyogenic liver abscessesCausesPMC12392612
UtiCausesPMC13014981
ColibacillosisCausesPMC13255289
Enteric infectionsCausesPMC13255289
Foodborne infectionsCausesPMC13255289
Clinical mastitisCausesPMC13293316
DiarrheaCausesPMC3035056

Displaying health effects 1 – 10 of 103 in total