Escherichia coli strain PNUSAE018269

Escherichia coli strain PNUSAE018269 is a Gram-negative, rod-shaped bacterium that exhibits mobility due to the presence of flagella. This strain is classified as a facultative anaerobe, allowing it to thrive in both aerobic and anaerobic environments. It is mesophilic, with an optimal growth temperature of 37°C, and typically resides in host-associated habitats. This strain has a diverse range of biotic relationships, being free-living and associated with various hosts, including Homo sapiens, Gallus gallus, Bos taurus, and numerous other vertebrate species, as well as certain plants like Solanum lycopersicum and Brassica oleracea var. italica. The presence of such a wide host range suggests that PNUSAE018269 may play significant roles in different ecological niches, influencing both animal health and agricultural systems. E. coli PNUSAE018269 is linked to numerous health effects, particularly in humans, where it is associated with urinary tract infections (UTIs), gastrointestinal infections, and severe conditions such as neonatal meningitis and hemolytic uremic syndrome (HUS). The strain can cause significant morbidity, manifesting in symptoms ranging from diarrhea to more severe complications like renal failure and sepsis. Given its pathogenicity profile and host associations, E. coli strain PNUSAE018269 underscores the importance of monitoring this bacterium in clinical and environmental contexts. Its capacity to cause diverse illnesses in multiple hosts highlights its role in both health and disease, necessitating further research to understand its impact on public health and ecosystems.