Escherichia coli strain FWSEC0595

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Escherichia

Description

Escherichia coli strain FWSEC0595 is a Gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic lifestyle, thriving optimally at a temperature of 37°C within the mesophilic range. This strain is characterized by its mobility, facilitated by the presence of flagella, and typically exists in pairs or as single cells. Notably, it possesses a single replicon and is surrounded by two membranes, typical of Gram-negative bacteria. FWSEC0595 is primarily host-associated, indicating a biotic relationship with various hosts, including Homo sapiens (humans), Gallus gallus (chickens), Bos taurus (cattle), and a range of other vertebrates and invertebrates. The strain is implicated in numerous health effects, particularly in humans, where it is associated with urinary tract infections (UTIs), gastrointestinal infections, and conditions such as neonatal meningitis and septicemia. The pathogenic potential of FWSEC0595 underscores its role as a significant pathogen in both clinical and environmental contexts. It can lead to serious health complications, including hemolytic uremic syndrome (HUS) and renal failure, particularly in vulnerable populations such as neonates. The strain’s diverse host range suggests that it may play a role in complex ecological interactions, contributing to the dynamics of microbial communities within various ecosystems. Understanding the characteristics and pathogenicity of E. coli strain FWSEC0595 can inform public health measures and strategies to mitigate its impact on human health and animal husbandry.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusEscherichia
SpeciesEscherichia coli
Strainstrain FWSEC0595

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Escherichia coli strain FWSEC0595
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Bos taurus
Cell arrangementPairs - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Escherichia coli strain FWSEC0595 plasmid unnamed2

Gene Summary

Adenine Count

1214719 bp

Thymine Count

1213335 bp

Guanine Count

1257605 bp

Cytosine Count

1249149 bp

Genome Length

4941373 bp

Protein-coding Genes

4533 genes

Non-Coding Genes

270 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
zinc transporter zuptC9326_01170Not AvailableNegative238841 - 23961426486.5
4,5-dopa dioxygenase extradiolC9326_01175Not AvailablePositive239730 - 24054529892.1
glutathionylspermidine synthase family proteinC9326_01180Not AvailableNegative240583 - 24174345028.4
duf1190 family proteinC9326_01185Not AvailableNegative241749 - 24242023480.7
outer membrane protein tolcC9326_01190Not AvailableNegative242568 - 24404953743.7
adp-ribose pyrophosphataseC9326_01195Not AvailablePositive244254 - 24488323668.2
duf1249 family proteinC9326_01200Not AvailablePositive244884 - 24530616549.0
3',5'-cyclic-amp phosphodiesteraseC9326_01205Not AvailablePositive245331 - 24615830939.7
esterase yqiaC9326_01210Not AvailablePositive246158 - 24673921642.7
dna topoisomerase iv subunit bC9326_01215Not AvailablePositive246768 - 24866070247.9

Displaying genes 451 – 460 of 4804 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

4785 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000173(R)-3-Hydroxybutyric acidC4H8O3Chemical structure of (R)-3-Hydroxybutyric acid625-72-3
Average104.0473Da
Monoisotopic104.047344122Da
BASm0000217alpha-ribazoleC14H18N2O4Chemical structure of alpha-ribazoleNot available
Average278.3037Da
Monoisotopic278.126657074Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm0000238(R)-3-phenyllactateC9H9O3Chemical structure of (R)-3-phenyllactateNot available
Average165.169Da
Monoisotopic165.05571773Da
BASm00002482,3-dihydroxy-3-methylbutanoateC5H10O4Chemical structure of 2,3-dihydroxy-3-methylbutanoate1756-18-9
Average134.1305Da
Monoisotopic134.0579088Da
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm00002593alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da
BASm00002603alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da

Displaying 1–10 of 4785 metabolites

Health Effects

Health ConditionRelationReference
Gi diseaseCausesPMC11149725
UtisCausesPMC11434687
Colorectal cancerCausesPMC12198655
Pyogenic liver abscessesCausesPMC12392612
UtiCausesPMC13014981
ColibacillosisCausesPMC13255289
Enteric infectionsCausesPMC13255289
Foodborne infectionsCausesPMC13255289
Clinical mastitisCausesPMC13293316
DiarrheaCausesPMC3035056

Displaying health effects 1 – 10 of 103 in total