Escherichia coli strain FWSEC0537

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Escherichia

Description

Escherichia coli strain FWSEC0537 is a Gram-negative, rod-shaped bacterium that exhibits facultative anaerobic metabolism. It typically forms pairs and singles and possesses flagella, allowing for mobility. This strain is mesophilic, with an optimal growth temperature of 37°C. It contains one replicon and has a characteristic double membrane structure. FWSEC0537 is primarily associated with hosts, including a diverse range of species such as Homo sapiens (humans), Gallus gallus (chickens), and Bos taurus (cattle), among others. This strain is classified as free-living, indicating that it can survive independently in various environments, although it frequently interacts with its hosts. The strain has been implicated in several health effects, particularly in humans, where it is associated with urinary tract infections (UTIs), gastrointestinal infections, and severe conditions such as neonatal meningitis and hemolytic uremic syndrome (HUS). The extensive list of health impacts also includes foodborne infections, peritonitis, and complications leading to renal failure and gastrointestinal diseases. The ecological significance of E. coli strain FWSEC0537 lies in its role as a pathogenic organism in both human and animal health. Its ability to thrive in various hosts suggests that it may play a role in the microbial dynamics of gut flora and the potential for zoonotic transmission of infections. This strain exemplifies the complexity of host-pathogen interactions and the impact of microbial pathogens on public health.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusEscherichia
SpeciesEscherichia coli
Strainstrain FWSEC0537

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Escherichia coli strain FWSEC0537
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Bos taurus
Cell arrangementPairs - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Escherichia coli strain FWSEC0537 plasmid unnamed7

Gene Summary

Adenine Count

1308128 bp

Thymine Count

1310798 bp

Guanine Count

1342120 bp

Cytosine Count

1315529 bp

Genome Length

5291545 bp

Protein-coding Genes

4973 genes

Non-Coding Genes

314 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
type 1 fimbrial proteinC9304_12870Not AvailablePositive2598581 - 259889211118.5
o-acetyl-adp-ribose deacetylaseC9304_12875Not AvailablePositive2598987 - 259952018837.4
phospholipase d family proteinC9304_12880Not AvailablePositive2599462 - 260094355929.7
glucan biosynthesis protein cC9304_12885Not AvailableNegative2600951 - 260210844702.9
glucan biosynthesis protein gC9304_12890Not AvailablePositive2602502 - 260403757885.4
glucan biosynthesis protein hC9304_12895Not AvailablePositive2604030 - 260657396942.7
ycek/yidq family lipoproteinC9304_12900Not AvailablePositive2606746 - 26069738443.31
acidic protein msybC9304_12905Not AvailableNegative2606974 - 260734814259.9
multidrug resistance protein mdtgC9304_12910Not AvailableNegative2607431 - 260865743870.0
lipid a biosynthesis lauroyltransferaseC9304_12915Not AvailableNegative2608829 - 260974935408.9

Displaying genes 2661 – 2670 of 5292 in total

Metabolites

4803 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000173(R)-3-Hydroxybutyric acidC4H8O3Chemical structure of (R)-3-Hydroxybutyric acid625-72-3
Average104.0473Da
Monoisotopic104.047344122Da
BASm0000217alpha-ribazoleC14H18N2O4Chemical structure of alpha-ribazoleNot available
Average278.3037Da
Monoisotopic278.126657074Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm0000238(R)-3-phenyllactateC9H9O3Chemical structure of (R)-3-phenyllactateNot available
Average165.169Da
Monoisotopic165.05571773Da
BASm00002482,3-dihydroxy-3-methylbutanoateC5H10O4Chemical structure of 2,3-dihydroxy-3-methylbutanoate1756-18-9
Average134.1305Da
Monoisotopic134.0579088Da
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm00002593alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da
BASm00002603alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da

Displaying 1–10 of 4803 metabolites

Health Effects

Health ConditionRelationReference
Gi diseaseCausesPMC11149725
UtisCausesPMC11434687
Colorectal cancerCausesPMC12198655
Pyogenic liver abscessesCausesPMC12392612
UtiCausesPMC13014981
ColibacillosisCausesPMC13255289
Enteric infectionsCausesPMC13255289
Foodborne infectionsCausesPMC13255289
Clinical mastitisCausesPMC13293316
DiarrheaCausesPMC3035056

Displaying health effects 1 – 10 of 103 in total