Escherichia coli strain FWSEC0527

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Escherichia

Description

Escherichia coli strain FWSEC0527 is a Gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic lifestyle and is motile due to the presence of flagella. This strain is primarily found in host-associated environments, indicating its reliance on various hosts for survival. It has a mesophilic temperature range, with an optimal growth temperature of 37°C, which aligns with the body temperature of many warm-blooded hosts. FWSEC0527 has been identified in a wide range of hosts including Homo sapiens (humans), Gallus gallus (chickens), and Bos taurus (cattle), among others. This diverse host range suggests a versatile ecological niche and the potential for cross-species transmission. The bacterium is associated with numerous health effects, notably urinary tract infections (UTIs), gastrointestinal infections, neonatal meningitis, and septicemia, among others. These health impacts highlight its pathogenic potential in humans and other animals, as well as its role in foodborne infections and diarrhea. With one replicon and two membranes, FWSEC0527 reflects the typical structure of E. coli, which is known for its adaptability in various environments. As a free-living organism, it plays a significant role in both health and disease dynamics within its host ecosystems. The various health issues associated with this strain, particularly in relation to urinary and gastrointestinal systems, underscore the importance of monitoring E. coli strains like FWSEC0527 for public health and veterinary concerns, as well as their ecological interactions within diverse microbiomes.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusEscherichia
SpeciesEscherichia coli
Strainstrain FWSEC0527

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Escherichia coli strain FWSEC0527
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Bos taurus
Cell arrangementPairs - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Escherichia coli strain FWSEC0527 plasmid unnamed4

Gene Summary

Adenine Count

1290723 bp

Thymine Count

1292403 bp

Guanine Count

1315691 bp

Cytosine Count

1315234 bp

Genome Length

5219416 bp

Protein-coding Genes

4641 genes

Non-Coding Genes

535 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
d-alanyl-d-alanine carboxypeptidaseC9296_18100Not AvailableNegative3657308 - 365851944446.5
endolytic peptidoglycan transglycosylase rlpaC9296_18105Not AvailableNegative3658659 - 365974737554.1
rod shape-determining protein rodaC9296_18110Not AvailableNegative3659758 - 366087040492.6
penicillin-binding protein 2C9296_18115Not AvailableNegative3660873 - 366277470860.6
23s rrna (pseudouridine(1915)-n(3))-methyltransferase rlmhC9296_18120Not AvailableNegative3662805 - 366327217342.1
ribosome silencing factor rsfsC9296_18125Not AvailableNegative3663276 - 366359311582.9
adenosylcobalamin/alpha-ribazole phosphataseC9296_18130Not AvailableNegative3663853 - 366446423418.8
nicotinate-nucleotide adenylyltransferaseC9296_18135Not AvailableNegative3664488 - 366512924513.3
dna polymerase iii subunit deltaC9296_18140Not AvailableNegative3665131 - 366616238722.0
lps assembly lipoprotein lpteC9296_18145Not AvailableNegative3666162 - 366674321357.8

Displaying genes 3741 – 3750 of 5177 in total

Metabolites

4785 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000173(R)-3-Hydroxybutyric acidC4H8O3Chemical structure of (R)-3-Hydroxybutyric acid625-72-3
Average104.0473Da
Monoisotopic104.047344122Da
BASm0000217alpha-ribazoleC14H18N2O4Chemical structure of alpha-ribazoleNot available
Average278.3037Da
Monoisotopic278.126657074Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm0000238(R)-3-phenyllactateC9H9O3Chemical structure of (R)-3-phenyllactateNot available
Average165.169Da
Monoisotopic165.05571773Da
BASm00002482,3-dihydroxy-3-methylbutanoateC5H10O4Chemical structure of 2,3-dihydroxy-3-methylbutanoate1756-18-9
Average134.1305Da
Monoisotopic134.0579088Da
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm00002593alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da
BASm00002603alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da

Displaying 1–10 of 4785 metabolites

Health Effects

Health ConditionRelationReference
Gi diseaseCausesPMC11149725
UtisCausesPMC11434687
Colorectal cancerCausesPMC12198655
Pyogenic liver abscessesCausesPMC12392612
UtiCausesPMC13014981
ColibacillosisCausesPMC13255289
Enteric infectionsCausesPMC13255289
Foodborne infectionsCausesPMC13255289
Clinical mastitisCausesPMC13293316
DiarrheaCausesPMC3035056

Displaying health effects 1 – 10 of 103 in total