Escherichia coli strain FWSEC0527

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Escherichia

Description

Escherichia coli strain FWSEC0527 is a Gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic lifestyle and is motile due to the presence of flagella. This strain is primarily found in host-associated environments, indicating its reliance on various hosts for survival. It has a mesophilic temperature range, with an optimal growth temperature of 37°C, which aligns with the body temperature of many warm-blooded hosts. FWSEC0527 has been identified in a wide range of hosts including Homo sapiens (humans), Gallus gallus (chickens), and Bos taurus (cattle), among others. This diverse host range suggests a versatile ecological niche and the potential for cross-species transmission. The bacterium is associated with numerous health effects, notably urinary tract infections (UTIs), gastrointestinal infections, neonatal meningitis, and septicemia, among others. These health impacts highlight its pathogenic potential in humans and other animals, as well as its role in foodborne infections and diarrhea. With one replicon and two membranes, FWSEC0527 reflects the typical structure of E. coli, which is known for its adaptability in various environments. As a free-living organism, it plays a significant role in both health and disease dynamics within its host ecosystems. The various health issues associated with this strain, particularly in relation to urinary and gastrointestinal systems, underscore the importance of monitoring E. coli strains like FWSEC0527 for public health and veterinary concerns, as well as their ecological interactions within diverse microbiomes.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusEscherichia
SpeciesEscherichia coli
Strainstrain FWSEC0527

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Escherichia coli strain FWSEC0527
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Bos taurus
Cell arrangementPairs - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Escherichia coli strain FWSEC0527 plasmid unnamed4

Gene Summary

Adenine Count

1290723 bp

Thymine Count

1292403 bp

Guanine Count

1315691 bp

Cytosine Count

1315234 bp

Genome Length

5219416 bp

Protein-coding Genes

4641 genes

Non-Coding Genes

535 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
cu(+)/ag(+) sensor histidine kinase cussC9296_17795Not AvailableNegative3591614 - 359305653779.3
copper response regulator transcription factor cusrC9296_17800Not AvailableNegative3593046 - 359372925396.1
efflux transporter outer membrane subunitC9296_17805Not AvailablePositive3593886 - 359526850739.9
cu(+)/ag(+) efflux rnd transporter periplasmic metallochaperone cusfC9296_17810Not AvailablePositive3595292 - 359562412210.8
cu(+)/ag(+) efflux rnd transporter periplasmic adaptor subunit cusbC9296_17815Not AvailablePositive3595640 - 359686344354.4
cu(+)/ag(+) efflux rnd transporter permease subunit cusaC9296_17820Not AvailablePositive3596875 - 3600018114706.0
aromatic amino acid transporter aropC9296_17825Not AvailablePositive3600120 - 360149650648.3
mechanosensitive ion channel family proteinC9296_17830Not AvailableNegative3601578 - 360282546639.5
oxygen-insensitive nad(p)h nitroreductaseC9296_17835Not AvailableNegative3602933 - 360358623994.4
mmcq/yjbr family dna-binding proteinC9296_17840Not AvailableNegative3603665 - 360404814638.7

Displaying genes 3681 – 3690 of 5177 in total

Metabolites

4785 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000173(R)-3-Hydroxybutyric acidC4H8O3Chemical structure of (R)-3-Hydroxybutyric acid625-72-3
Average104.0473Da
Monoisotopic104.047344122Da
BASm0000217alpha-ribazoleC14H18N2O4Chemical structure of alpha-ribazoleNot available
Average278.3037Da
Monoisotopic278.126657074Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm0000238(R)-3-phenyllactateC9H9O3Chemical structure of (R)-3-phenyllactateNot available
Average165.169Da
Monoisotopic165.05571773Da
BASm00002482,3-dihydroxy-3-methylbutanoateC5H10O4Chemical structure of 2,3-dihydroxy-3-methylbutanoate1756-18-9
Average134.1305Da
Monoisotopic134.0579088Da
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm00002593alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da
BASm00002603alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da

Displaying 1–10 of 4785 metabolites

Health Effects

Health ConditionRelationReference
Gi diseaseCausesPMC11149725
UtisCausesPMC11434687
Colorectal cancerCausesPMC12198655
Pyogenic liver abscessesCausesPMC12392612
UtiCausesPMC13014981
ColibacillosisCausesPMC13255289
Enteric infectionsCausesPMC13255289
Foodborne infectionsCausesPMC13255289
Clinical mastitisCausesPMC13293316
DiarrheaCausesPMC3035056

Displaying health effects 1 – 10 of 103 in total