Escherichia coli strain FWSEC0443

Escherichia coli strain FWSEC0443 is a Gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic lifestyle, enabling it to thrive in varying oxygen conditions. This strain is motile and possesses flagella, facilitating its movement. It is mesophilic, with an optimal growth temperature of 37°C, which aligns with the body temperature of many host organisms. FWSEC0443 is primarily host-associated, exhibiting a diverse range of biotic relationships with various hosts, including Homo sapiens (humans), Gallus gallus (chickens), and Bos taurus (cattle), among many others. Its capacity to infect a wide variety of species, including mammals, birds, and even certain plants, highlights its ecological versatility. This strain is notably associated with numerous health effects in humans, including urinary tract infections (UTIs), gastrointestinal infections, and neonatal meningitis. It can cause severe conditions such as septicemia, hemolytic uremic syndrome (HUS), and even complications leading to renal failure. The extensive list of pathogenic outcomes emphasizes its significant role in clinical settings, contributing to foodborne infections and hospital-acquired diseases. Given its pathogenic potential and the variety of hosts it affects, E. coli strain FWSEC0443 presents an important consideration in both public health and veterinary medicine. Its ability to engage with such a wide range of organisms not only demonstrates its adaptability but also underscores the need for continued surveillance and research into its impact on human and animal health.