Escherichia coli strain FWSEC0439

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Escherichia

Description

Escherichia coli strain FWSEC0439 is a Gram-negative, rod-shaped bacterium that exhibits mobility, facilitated by the presence of flagella. This strain is classified as a facultative anaerobe, allowing it to thrive in both aerobic and anaerobic environments. It typically resides in host-associated habitats, with a broad range of hosts including Homo sapiens, various livestock such as Bos taurus and Sus scrofa, as well as numerous other vertebrate and invertebrate species. FWSEC0439 has a mesophilic growth range, with an optimal temperature of 37°C. It possesses a single replicon and a double membrane structure, consistent with its classification in the Enterobacteriaceae family. Its biotic relationship is characterized as free-living, indicating its ability to survive independently of a host under certain conditions. This strain is notably pathogenic to humans, associated with a variety of health issues including urinary tract infections (UTIs), gastrointestinal infections, and severe conditions such as hemolytic uremic syndrome (HUS) and neonatal meningitis. The diverse range of diseases it can cause underscores its significant public health impact. The ecological insight from studying E. coli strain FWSEC0439 is its adaptability and versatility in different environments, which allows it to infect a wide array of hosts and cause various diseases. This adaptability may contribute to its persistence in both natural and clinical settings, highlighting the importance of monitoring and understanding such pathogenic strains in the context of health and disease management.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusEscherichia
SpeciesEscherichia coli
Strainstrain FWSEC0439

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Escherichia coli strain FWSEC0439
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Bos taurus
Cell arrangementPairs - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Escherichia coli strain FWSEC0439 plasmid unnamed6

Gene Summary

Adenine Count

1267388 bp

Thymine Count

1267027 bp

Guanine Count

1288249 bp

Cytosine Count

1285886 bp

Genome Length

5120665 bp

Protein-coding Genes

4747 genes

Non-Coding Genes

229 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
penicillin-binding protein 2C9214_12275Not AvailablePositive2521054 - 252295570860.6
rod shape-determining protein rodaC9214_12280Not AvailablePositive2522958 - 252407040478.6
endolytic peptidoglycan transglycosylase rlpaC9214_12285Not AvailablePositive2524081 - 252516937502.0
d-alanyl-d-alanine carboxypeptidaseC9214_12290Not AvailablePositive2525308 - 252651944446.5
duf493 family proteinC9214_12295Not AvailablePositive2526630 - 25268939827.92
lipoyl(octanoyl) transferase lipbC9214_12300Not AvailablePositive2526994 - 252763523883.0
dna-binding transcriptional regulatorC9214_12305Not AvailablePositive2527894 - 252884735958.5
lipoyl synthaseC9214_12310Not AvailablePositive2529056 - 253002136073.8
twin-arginine translocase subunit tateC9214_12315Not AvailableNegative2530122 - 25303257024.71
hydrolase ybemC9214_12320Not AvailableNegative2530454 - 253124228713.1

Displaying genes 2551 – 2560 of 4979 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

4785 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000173(R)-3-Hydroxybutyric acidC4H8O3Chemical structure of (R)-3-Hydroxybutyric acid625-72-3
Average104.0473Da
Monoisotopic104.047344122Da
BASm0000217alpha-ribazoleC14H18N2O4Chemical structure of alpha-ribazoleNot available
Average278.3037Da
Monoisotopic278.126657074Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm0000238(R)-3-phenyllactateC9H9O3Chemical structure of (R)-3-phenyllactateNot available
Average165.169Da
Monoisotopic165.05571773Da
BASm00002482,3-dihydroxy-3-methylbutanoateC5H10O4Chemical structure of 2,3-dihydroxy-3-methylbutanoate1756-18-9
Average134.1305Da
Monoisotopic134.0579088Da
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm00002593alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da
BASm00002603alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da

Displaying 1–10 of 4785 metabolites

Health Effects

Health ConditionRelationReference
Gi diseaseCausesPMC11149725
UtisCausesPMC11434687
Colorectal cancerCausesPMC12198655
Pyogenic liver abscessesCausesPMC12392612
UtiCausesPMC13014981
ColibacillosisCausesPMC13255289
Enteric infectionsCausesPMC13255289
Foodborne infectionsCausesPMC13255289
Clinical mastitisCausesPMC13293316
DiarrheaCausesPMC3035056

Displaying health effects 1 – 10 of 103 in total