Escherichia coli strain FWSEC0438

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Escherichia

Description

Escherichia coli strain FWSEC0438 is a Gram-negative, rod-shaped bacterium that exhibits mobility due to the presence of flagella. It is classified as a facultative anaerobe, allowing it to thrive in both aerobic and anaerobic environments. The strain is mesophilic, with an optimal growth temperature of 37°C, making it well-suited for survival within warm-blooded hosts. FWSEC0438 is host-associated and demonstrates a free-living biotic relationship. It has a wide range of hosts, including Homo sapiens (humans), Gallus gallus (chickens), Bos taurus (cattle), various mammals, and even some plants such as Solanum lycopersicum (tomato) and Brassica oleracea var. italica (broccoli). This extensive host range suggests a significant ecological adaptability, allowing the strain to inhabit diverse environments. The strain is associated with numerous health effects, particularly in humans, where it is linked to urinary tract infections (UTIs), gastrointestinal infections, and more severe conditions such as neonatal meningitis and hemolytic uremic syndrome (HUS). The pathogenicity of FWSEC0438 in humans raises concerns about its role in foodborne illnesses and other infections. This bacterium's ability to thrive in various hosts and environments, coupled with its pathogenic potential, underscores its ecological significance. Understanding the interactions between E. coli FWSEC0438 and its diverse hosts can provide insights into disease prevention and control strategies, particularly in the context of public health and food safety.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusEscherichia
SpeciesEscherichia coli
Strainstrain FWSEC0438

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Escherichia coli strain FWSEC0438
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Bos taurus
Cell arrangementPairs - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Escherichia coli strain FWSEC0438 FWSEC0438_contig00122, whole

Gene Summary

Adenine Count

1201139 bp

Thymine Count

1202681 bp

Guanine Count

1219253 bp

Cytosine Count

1230952 bp

Genome Length

4862979 bp

Protein-coding Genes

4391 genes

Non-Coding Genes

204 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
dna-binding transcriptional regulator fisC9213_17940Not AvailablePositive3685819 - 368611511240.6
adenine-specific dna-methyltransferaseC9213_17945Not AvailablePositive3686201 - 368708533399.3
duf2556 domain-containing proteinC9213_17950Not AvailablePositive3687169 - 36873487203.93
multidrug efflux transporter transcriptional repressor acrsC9213_17955Not AvailableNegative3687351 - 368801325199.7
multidrug efflux rnd transporter periplasmic adaptor subunit acreC9213_17960Not AvailablePositive3688412 - 368956941320.0
multidrug efflux rnd transporter permease subunit acrfC9213_17965Not AvailablePositive3689581 - 3692685111461.0
hypothetical proteinC9213_17970Not AvailablePositive3692938 - 36931597452.14
amino acid abc transporter substrate-binding proteinC9213_17975Not AvailablePositive3693590 - 369461537048.9
amino acid abc transporter permeaseC9213_17980Not AvailablePositive3694683 - 369586443263.9
amino acid abc transporter permeaseC9213_17985Not AvailablePositive3695874 - 369697741486.7

Displaying genes 3611 – 3620 of 4655 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

4785 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000173(R)-3-Hydroxybutyric acidC4H8O3Chemical structure of (R)-3-Hydroxybutyric acid625-72-3
Average104.0473Da
Monoisotopic104.047344122Da
BASm0000217alpha-ribazoleC14H18N2O4Chemical structure of alpha-ribazoleNot available
Average278.3037Da
Monoisotopic278.126657074Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm0000238(R)-3-phenyllactateC9H9O3Chemical structure of (R)-3-phenyllactateNot available
Average165.169Da
Monoisotopic165.05571773Da
BASm00002482,3-dihydroxy-3-methylbutanoateC5H10O4Chemical structure of 2,3-dihydroxy-3-methylbutanoate1756-18-9
Average134.1305Da
Monoisotopic134.0579088Da
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm00002593alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da
BASm00002603alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da

Displaying 1–10 of 4785 metabolites

Health Effects

Health ConditionRelationReference
Gi diseaseCausesPMC11149725
UtisCausesPMC11434687
Colorectal cancerCausesPMC12198655
Pyogenic liver abscessesCausesPMC12392612
UtiCausesPMC13014981
ColibacillosisCausesPMC13255289
Enteric infectionsCausesPMC13255289
Foodborne infectionsCausesPMC13255289
Clinical mastitisCausesPMC13293316
DiarrheaCausesPMC3035056

Displaying health effects 1 – 10 of 103 in total