Escherichia coli strain FWSEC0438

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Escherichia

Description

Escherichia coli strain FWSEC0438 is a Gram-negative, rod-shaped bacterium that exhibits mobility due to the presence of flagella. It is classified as a facultative anaerobe, allowing it to thrive in both aerobic and anaerobic environments. The strain is mesophilic, with an optimal growth temperature of 37°C, making it well-suited for survival within warm-blooded hosts. FWSEC0438 is host-associated and demonstrates a free-living biotic relationship. It has a wide range of hosts, including Homo sapiens (humans), Gallus gallus (chickens), Bos taurus (cattle), various mammals, and even some plants such as Solanum lycopersicum (tomato) and Brassica oleracea var. italica (broccoli). This extensive host range suggests a significant ecological adaptability, allowing the strain to inhabit diverse environments. The strain is associated with numerous health effects, particularly in humans, where it is linked to urinary tract infections (UTIs), gastrointestinal infections, and more severe conditions such as neonatal meningitis and hemolytic uremic syndrome (HUS). The pathogenicity of FWSEC0438 in humans raises concerns about its role in foodborne illnesses and other infections. This bacterium's ability to thrive in various hosts and environments, coupled with its pathogenic potential, underscores its ecological significance. Understanding the interactions between E. coli FWSEC0438 and its diverse hosts can provide insights into disease prevention and control strategies, particularly in the context of public health and food safety.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusEscherichia
SpeciesEscherichia coli
Strainstrain FWSEC0438

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Escherichia coli strain FWSEC0438
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Bos taurus
Cell arrangementPairs - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Escherichia coli strain FWSEC0438 FWSEC0438_contig00122, whole

Gene Summary

Adenine Count

1201139 bp

Thymine Count

1202681 bp

Guanine Count

1219253 bp

Cytosine Count

1230952 bp

Genome Length

4862979 bp

Protein-coding Genes

4391 genes

Non-Coding Genes

204 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
l-2-hydroxyglutarate oxidaseC9213_15645Not AvailablePositive3210333 - 321160146070.6
nadp-dependent succinate-semialdehyde dehydrogenase iC9213_15650Not AvailablePositive3211624 - 321307251723.0
4-aminobutyrate aminotransferase gabtC9213_15655Not AvailablePositive3213086 - 321436645777.3
gaba permeaseC9213_15660Not AvailablePositive3214604 - 321600451083.1
transcriptional regulatorC9213_15665Not AvailablePositive3216025 - 321668724992.3
peptidoglycan-binding protein lysmC9213_15670Not AvailableNegative3216688 - 321713716064.0
yqae/pmp3 family membrane proteinC9213_15675Not AvailableNegative3217221 - 32173795865.57
transcriptional regulatorC9213_15680Not AvailablePositive3217562 - 321786110596.9
thiosulfate sulfurtransferase ygapC9213_15685Not AvailablePositive3217871 - 321839518639.8
dna-binding protein stpaC9213_15690Not AvailableNegative3218442 - 321884615348.4

Displaying genes 3171 – 3180 of 4655 in total

Metabolites

4785 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000173(R)-3-Hydroxybutyric acidC4H8O3Chemical structure of (R)-3-Hydroxybutyric acid625-72-3
Average104.0473Da
Monoisotopic104.047344122Da
BASm0000217alpha-ribazoleC14H18N2O4Chemical structure of alpha-ribazoleNot available
Average278.3037Da
Monoisotopic278.126657074Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm0000238(R)-3-phenyllactateC9H9O3Chemical structure of (R)-3-phenyllactateNot available
Average165.169Da
Monoisotopic165.05571773Da
BASm00002482,3-dihydroxy-3-methylbutanoateC5H10O4Chemical structure of 2,3-dihydroxy-3-methylbutanoate1756-18-9
Average134.1305Da
Monoisotopic134.0579088Da
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm00002593alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da
BASm00002603alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da

Displaying 1–10 of 4785 metabolites

Health Effects

Health ConditionRelationReference
Gi diseaseCausesPMC11149725
UtisCausesPMC11434687
Colorectal cancerCausesPMC12198655
Pyogenic liver abscessesCausesPMC12392612
UtiCausesPMC13014981
ColibacillosisCausesPMC13255289
Enteric infectionsCausesPMC13255289
Foodborne infectionsCausesPMC13255289
Clinical mastitisCausesPMC13293316
DiarrheaCausesPMC3035056

Displaying health effects 1 – 10 of 103 in total