Escherichia coli strain FWSEC0427

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Escherichia

Description

Escherichia coli strain FWSEC0427 is a Gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic metabolism. This strain is capable of mobility due to the presence of flagella and typically arranges itself in pairs or singles. It thrives at an optimal temperature of 37°C, which corresponds to its classification as mesophilic. FWSEC0427 is host-associated, with a diverse range of hosts including Homo sapiens (humans), Gallus gallus (chickens), Bos taurus (cattle), and various species across multiple taxa such as Mammalia, Aves, and even invertebrates like Apis mellifera (honeybees) and mollusks. This wide host range suggests that FWSEC0427 has a significant ecological versatility and adaptability. The strain is known for its pathogenicity in humans, being associated with a variety of health issues including urinary tract infections (UTIs), gastrointestinal infections, and severe conditions like hemolytic uremic syndrome (HUS). Additionally, it has been implicated in neonatal meningitis and various forms of septicemia. The extensive list of health effects attributed to FWSEC0427 underscores its relevance in clinical microbiology and public health. The ability of FWSEC0427 to thrive in diverse environments and its association with significant health impacts highlight the importance of monitoring such strains in both human health and agricultural contexts. Understanding the interactions between FWSEC0427 and its various hosts can provide insights into the mechanisms of pathogenicity and the potential for outbreaks in different populations.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusEscherichia
SpeciesEscherichia coli
Strainstrain FWSEC0427

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Escherichia coli strain FWSEC0427
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Bos taurus
Cell arrangementPairs - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Escherichia coli strain FWSEC0427 plasmid unnamed4

Gene Summary

Adenine Count

1310908 bp

Thymine Count

1315685 bp

Guanine Count

1348365 bp

Cytosine Count

1325084 bp

Genome Length

5310772 bp

Protein-coding Genes

4966 genes

Non-Coding Genes

306 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
upf0259 family proteinC9202_13160Not AvailablePositive2726820 - 272756326434.6
septation protein aC9202_13165Not AvailablePositive2727593 - 272813220791.3
acyl-coa thioester hydrolase yciaC9202_13170Not AvailablePositive2728237 - 272863514231.4
tonb system transport protein tonbC9202_13175Not AvailableNegative2728675 - 272939426037.6
ycii family proteinC9202_13180Not AvailablePositive2729618 - 272991410602.6
voltage-gated potassium channel proteinC9202_13185Not AvailablePositive2730214 - 273146746080.2
yciy family proteinC9202_13190Not AvailableNegative2731522 - 27316957102.81
cardiolipin synthaseC9202_13195Not AvailablePositive2731838 - 273329854825.6
duf440 family proteinC9202_13200Not AvailablePositive2733333 - 273366212687.7
oligopeptide transport atp-binding protein oppfC9202_13205Not AvailableNegative2733715 - 273471937183.8

Displaying genes 2831 – 2840 of 5275 in total

Metabolites

4617 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000173(R)-3-Hydroxybutyric acidC4H8O3Chemical structure of (R)-3-Hydroxybutyric acid625-72-3
Average104.0473Da
Monoisotopic104.047344122Da
BASm0000217alpha-ribazoleC14H18N2O4Chemical structure of alpha-ribazoleNot available
Average278.3037Da
Monoisotopic278.126657074Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm0000238(R)-3-phenyllactateC9H9O3Chemical structure of (R)-3-phenyllactateNot available
Average165.169Da
Monoisotopic165.05571773Da
BASm00002482,3-dihydroxy-3-methylbutanoateC5H10O4Chemical structure of 2,3-dihydroxy-3-methylbutanoate1756-18-9
Average134.1305Da
Monoisotopic134.0579088Da
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm00002593alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da
BASm00002603alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da

Displaying 1–10 of 4617 metabolites

Health Effects

Health ConditionRelationReference
Gi diseaseCausesPMC11149725
UtisCausesPMC11434687
Colorectal cancerCausesPMC12198655
Pyogenic liver abscessesCausesPMC12392612
UtiCausesPMC13014981
ColibacillosisCausesPMC13255289
Enteric infectionsCausesPMC13255289
Foodborne infectionsCausesPMC13255289
Clinical mastitisCausesPMC13293316
DiarrheaCausesPMC3035056

Displaying health effects 1 – 10 of 103 in total