Escherichia coli strain FWSEC0427

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Escherichia

Description

Escherichia coli strain FWSEC0427 is a Gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic metabolism. This strain is capable of mobility due to the presence of flagella and typically arranges itself in pairs or singles. It thrives at an optimal temperature of 37°C, which corresponds to its classification as mesophilic. FWSEC0427 is host-associated, with a diverse range of hosts including Homo sapiens (humans), Gallus gallus (chickens), Bos taurus (cattle), and various species across multiple taxa such as Mammalia, Aves, and even invertebrates like Apis mellifera (honeybees) and mollusks. This wide host range suggests that FWSEC0427 has a significant ecological versatility and adaptability. The strain is known for its pathogenicity in humans, being associated with a variety of health issues including urinary tract infections (UTIs), gastrointestinal infections, and severe conditions like hemolytic uremic syndrome (HUS). Additionally, it has been implicated in neonatal meningitis and various forms of septicemia. The extensive list of health effects attributed to FWSEC0427 underscores its relevance in clinical microbiology and public health. The ability of FWSEC0427 to thrive in diverse environments and its association with significant health impacts highlight the importance of monitoring such strains in both human health and agricultural contexts. Understanding the interactions between FWSEC0427 and its various hosts can provide insights into the mechanisms of pathogenicity and the potential for outbreaks in different populations.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusEscherichia
SpeciesEscherichia coli
Strainstrain FWSEC0427

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Escherichia coli strain FWSEC0427
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Bos taurus
Cell arrangementPairs - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Escherichia coli strain FWSEC0427 plasmid unnamed4

Gene Summary

Adenine Count

1310908 bp

Thymine Count

1315685 bp

Guanine Count

1348365 bp

Cytosine Count

1325084 bp

Genome Length

5310772 bp

Protein-coding Genes

4966 genes

Non-Coding Genes

306 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
hth-type transcriptional regulator gntrC9202_08250Not AvailableNegative1746423 - 174741836424.2
quercetin 2,3-dioxygenaseC9202_08255Not AvailableNegative1747642 - 174833726280.8
oxidoreductaseC9202_08260Not AvailableNegative1748460 - 174949738767.1
n-acetyltransferaseC9202_08265Not AvailablePositive1749829 - 175031718794.6
hcp1 family type vi secretion system effectorC9202_08270Not AvailablePositive1750554 - 175173244306.9
hypothetical proteinC9202_08275Not AvailablePositive1751729 - 175222319018.5
hypothetical proteinC9202_08280Not AvailablePositive1752318 - 17524736027.24
hypothetical proteinC9202_08285Not AvailablePositive1752537 - 17527197192.6
hypothetical proteinC9202_08290Not AvailablePositive1752673 - 175295710613.4
gamma-glutamyltranspeptidaseC9202_08295Not AvailableNegative1752995 - 175473761802.5

Displaying genes 1901 – 1910 of 5275 in total

Metabolites

4785 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000173(R)-3-Hydroxybutyric acidC4H8O3Chemical structure of (R)-3-Hydroxybutyric acid625-72-3
Average104.0473Da
Monoisotopic104.047344122Da
BASm0000217alpha-ribazoleC14H18N2O4Chemical structure of alpha-ribazoleNot available
Average278.3037Da
Monoisotopic278.126657074Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm0000238(R)-3-phenyllactateC9H9O3Chemical structure of (R)-3-phenyllactateNot available
Average165.169Da
Monoisotopic165.05571773Da
BASm00002482,3-dihydroxy-3-methylbutanoateC5H10O4Chemical structure of 2,3-dihydroxy-3-methylbutanoate1756-18-9
Average134.1305Da
Monoisotopic134.0579088Da
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm00002593alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da
BASm00002603alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da

Displaying 1–10 of 4785 metabolites

Health Effects

Health ConditionRelationReference
Gi diseaseCausesPMC11149725
UtisCausesPMC11434687
Colorectal cancerCausesPMC12198655
Pyogenic liver abscessesCausesPMC12392612
UtiCausesPMC13014981
ColibacillosisCausesPMC13255289
Enteric infectionsCausesPMC13255289
Foodborne infectionsCausesPMC13255289
Clinical mastitisCausesPMC13293316
DiarrheaCausesPMC3035056

Displaying health effects 1 – 10 of 103 in total