Escherichia coli strain FWSEC0423

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Escherichia

Description

Escherichia coli strain FWSEC0423 is a Gram-negative, rod-shaped bacterium that is classified as a facultative anaerobe, allowing it to thrive in environments with or without oxygen. This strain exhibits mobility due to the presence of flagella and typically exists in pairs or as single cells. Its optimal growth temperature is 37°C, placing it within the mesophilic temperature range. FWSEC0423 is associated with a variety of hosts, including Homo sapiens (humans) and domesticated animals such as Gallus gallus (chickens) and Bos taurus (cattle), as well as other vertebrates and invertebrates. This broad host range indicates its versatility in different biological and ecological contexts. The strain is noted for its pathogenicity in humans, being linked to a wide array of health effects. These include urinary tract infections (UTIs), gastrointestinal infections, neonatal meningitis, and even more severe conditions such as hemolytic uremic syndrome (HUS) and peritonitis. The diverse health implications highlight its role as a significant pathogen in both community and nosocomial settings. FWSEC0423’s biotic relationship is categorized as free-living, suggesting it can survive independently in its environment while also being associated with various hosts. This duality allows it to play a complex role in host-pathogen interactions, influencing both health and disease dynamics in both humans and animals. Understanding the traits and pathogenic potential of FWSEC0423 underscores the importance of monitoring its spread and impact on public health.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusEscherichia
SpeciesEscherichia coli
Strainstrain FWSEC0423

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Escherichia coli strain FWSEC0423
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Bos taurus
Cell arrangementPairs - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Escherichia coli strain FWSEC0423 plasmid unnamed11

Gene Summary

Adenine Count

1327677 bp

Thymine Count

1331023 bp

Guanine Count

1372307 bp

Cytosine Count

1362293 bp

Genome Length

5403282 bp

Protein-coding Genes

4884 genes

Non-Coding Genes

449 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
AttrNot AvailableNot AvailablePositive812592 - 812603Not Available
Tyrosine-type recombinase/integraseC9198_04005Not AvailablePositive812705 - 81369737956.9
Dimethyl sulfoxide reductase dmsaC9198_04010Not AvailablePositive813997 - 81644190366.6
Anaerobic dimethyl sulfoxide reductase subunit bC9198_04015Not AvailablePositive816452 - 81706922870.1
Dmso reductase anchor subunit cC9198_04020Not AvailablePositive817071 - 81793430862.2
Lysozyme peptidaseC9198_05075Not AvailablePositive1048337 - 104909226540.0
Trna,type:gly,anti_codon:ccc;Not AvailableNot AvailablePositive1049171 - 1049244Not Available
AttlNot AvailableNot AvailablePositive1049394 - 1049405Not Available
Putative prophage integraseC9198_05085Not AvailablePositive1049409 - 105062346471.1
Putative repressor proteinC9198_05090Not AvailablePositive1051167 - 10513707730.26

Displaying genes 71 – 80 of 5336 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

4785 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000173(R)-3-Hydroxybutyric acidC4H8O3Chemical structure of (R)-3-Hydroxybutyric acid625-72-3
Average104.0473Da
Monoisotopic104.047344122Da
BASm0000217alpha-ribazoleC14H18N2O4Chemical structure of alpha-ribazoleNot available
Average278.3037Da
Monoisotopic278.126657074Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm0000238(R)-3-phenyllactateC9H9O3Chemical structure of (R)-3-phenyllactateNot available
Average165.169Da
Monoisotopic165.05571773Da
BASm00002482,3-dihydroxy-3-methylbutanoateC5H10O4Chemical structure of 2,3-dihydroxy-3-methylbutanoate1756-18-9
Average134.1305Da
Monoisotopic134.0579088Da
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm00002593alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da
BASm00002603alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da

Displaying 1–10 of 4785 metabolites

Health Effects

Health ConditionRelationReference
Gi diseaseCausesPMC11149725
UtisCausesPMC11434687
Colorectal cancerCausesPMC12198655
Pyogenic liver abscessesCausesPMC12392612
UtiCausesPMC13014981
ColibacillosisCausesPMC13255289
Enteric infectionsCausesPMC13255289
Foodborne infectionsCausesPMC13255289
Clinical mastitisCausesPMC13293316
DiarrheaCausesPMC3035056

Displaying health effects 1 – 10 of 103 in total