Escherichia coli strain FWSEC0418

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Escherichia

Description

Escherichia coli strain FWSEC0418 is a Gram-negative, rod-shaped bacterium characterized by its facultative anaerobic metabolism and motility, facilitated by the presence of flagella. This strain is adapted to a host-associated habitat, primarily living free in various environments. It exhibits an optimal growth temperature of 37°C and is classified as mesophilic, thriving within a moderate temperature range. FWSEC0418 is associated with numerous hosts, including Homo sapiens, Gallus gallus, Bos taurus, and various other vertebrates and invertebrates. Its extensive host range indicates a versatile ecological role, potentially affecting multiple species and ecosystems. The strain is linked to a variety of health effects in humans and animals, including urinary tract infections (UTIs), gastrointestinal infections, and more severe conditions such as neonatal meningitis and hemolytic uremic syndrome (HUS). The presence of such a wide array of pathogenic effects underscores the strain's significant impact on health, particularly regarding foodborne illnesses and infections. The biological insight from the characteristics of FWSEC0418 highlights the strain's potential as a critical pathogen in both human and veterinary medicine. Its ability to inhabit diverse hosts and cause various infections illustrates the importance of monitoring this strain in public health and food safety contexts. Understanding its pathogenic mechanisms and host interactions can inform strategies to mitigate its effects on health and prevent outbreaks associated with foodborne infections.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusEscherichia
SpeciesEscherichia coli
Strainstrain FWSEC0418

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Escherichia coli strain FWSEC0418
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Bos taurus
Cell arrangementPairs - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Escherichia coli strain FWSEC0418 plasmid unnamed2

Gene Summary

Adenine Count

1245845 bp

Thymine Count

1245298 bp

Guanine Count

1274282 bp

Cytosine Count

1287477 bp

Genome Length

5059722 bp

Protein-coding Genes

4588 genes

Non-Coding Genes

348 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
AttlNot AvailableNot AvailablePositive1821206 - 1821219Not Available
Hypothetical proteinC9193_08710Not AvailableNegative1821551 - 182184110799.0
Hypothetical proteinC9193_08715Not AvailableNegative1821865 - 18220567718.17
Dna recombination proteinC9193_08720Not AvailableNegative1822053 - 182246315642.8
Antirepressor proteinC9193_08725Not AvailableNegative1822518 - 182318626041.5
Putative membrane proteinC9193_08730Not AvailablePositive1823532 - 182390614679.0
Hypothetical proteinC9193_08735Not AvailableNegative1823926 - 182459726420.6
Hypothetical proteinC9193_08740Not AvailableNegative1824609 - 182503416524.9
Hypothetical proteinC9193_08745Not AvailablePositive1825263 - 182559212836.7
Helix-turn-helix family proteinC9193_08750Not AvailablePositive1825582 - 182589011186.6

Displaying genes 51 – 60 of 4943 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

4785 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000173(R)-3-Hydroxybutyric acidC4H8O3Chemical structure of (R)-3-Hydroxybutyric acid625-72-3
Average104.0473Da
Monoisotopic104.047344122Da
BASm0000217alpha-ribazoleC14H18N2O4Chemical structure of alpha-ribazoleNot available
Average278.3037Da
Monoisotopic278.126657074Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm0000238(R)-3-phenyllactateC9H9O3Chemical structure of (R)-3-phenyllactateNot available
Average165.169Da
Monoisotopic165.05571773Da
BASm00002482,3-dihydroxy-3-methylbutanoateC5H10O4Chemical structure of 2,3-dihydroxy-3-methylbutanoate1756-18-9
Average134.1305Da
Monoisotopic134.0579088Da
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm00002593alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da
BASm00002603alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da

Displaying 1–10 of 4785 metabolites

Health Effects

Health ConditionRelationReference
Gi diseaseCausesPMC11149725
UtisCausesPMC11434687
Colorectal cancerCausesPMC12198655
Pyogenic liver abscessesCausesPMC12392612
UtiCausesPMC13014981
ColibacillosisCausesPMC13255289
Enteric infectionsCausesPMC13255289
Foodborne infectionsCausesPMC13255289
Clinical mastitisCausesPMC13293316
DiarrheaCausesPMC3035056

Displaying health effects 1 – 10 of 103 in total