Escherichia coli strain FWSEC0414

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Escherichia

Description

Escherichia coli strain FWSEC0414 is a gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic metabolism, allowing it to thrive in various oxygen conditions. It typically forms pairs or single cells and possesses flagella, which confer motility. This strain is classified as mesophilic, with an optimal growth temperature of 37°C, making it well-suited for its primary habitats, which include a variety of host-associated environments. FWSEC0414 has a diverse range of hosts, including Homo sapiens, Gallus gallus, and several mammals such as Bos taurus and Sus scrofa, as well as plants like Solanum lycopersicum and Brassica oleracea var. italica. This extensive host range indicates its adaptability and potential ecological significance across different biological systems. The strain is associated with a variety of health effects, notably including urinary tract infections (UTIs), gastrointestinal infections, and severe conditions such as neonatal meningitis and hemolytic uremic syndrome (HUS). This pathogenicity in humans highlights its role as a significant opportunistic pathogen, capable of causing a spectrum of diseases ranging from mild diarrhea to life-threatening infections. Given its free-living biotic relationship and ability to infect multiple hosts, FWSEC0414 exemplifies the complexities of microbial interactions within diverse ecosystems. Its presence in both animal and plant hosts suggests a significant ecological role, potentially affecting both health and environmental dynamics through its pathogenic capabilities and interactions with host immune responses.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusEscherichia
SpeciesEscherichia coli
Strainstrain FWSEC0414

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Escherichia coli strain FWSEC0414
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Bos taurus
Cell arrangementPairs - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Escherichia coli strain FWSEC0414 plasmid unnamed2

Gene Summary

Adenine Count

1306843 bp

Thymine Count

1310177 bp

Guanine Count

1321151 bp

Cytosine Count

1326769 bp

Genome Length

5277330 bp

Protein-coding Genes

4840 genes

Non-Coding Genes

457 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
monofunctional biosynthetic peptidoglycan transglycosylaseC9189_06920Not AvailablePositive1472687 - 147341527343.1
phop regulatory network protein yrblC9189_06925Not AvailableNegative1473412 - 147404424346.4
phosphocarrier protein nprC9189_06930Not AvailableNegative1474258 - 14745309810.71
rnase adaptor protein rapzC9189_06935Not AvailableNegative1474527 - 147538132494.2
pts iia-like nitrogen regulatory protein ptsnC9189_06940Not AvailableNegative1475427 - 147591817960.6
ribosome hibernation promoting factorC9189_06945Not AvailableNegative1476036 - 147632310750.9
rna polymerase factor sigma-54C9189_06950Not AvailableNegative1476346 - 147777954054.9
lipopolysaccharide abc transporter atp-binding proteinC9189_06955Not AvailableNegative1477827 - 147855226802.3
lipopolysaccharide abc transporter substrate-binding protein lptaC9189_06960Not AvailableNegative1478559 - 147911620128.1
lps export abc transporter periplasmic protein lptcC9189_06965Not AvailableNegative1479085 - 147966021703.8

Displaying genes 1831 – 1840 of 5302 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

4785 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000173(R)-3-Hydroxybutyric acidC4H8O3Chemical structure of (R)-3-Hydroxybutyric acid625-72-3
Average104.0473Da
Monoisotopic104.047344122Da
BASm0000217alpha-ribazoleC14H18N2O4Chemical structure of alpha-ribazoleNot available
Average278.3037Da
Monoisotopic278.126657074Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm0000238(R)-3-phenyllactateC9H9O3Chemical structure of (R)-3-phenyllactateNot available
Average165.169Da
Monoisotopic165.05571773Da
BASm00002482,3-dihydroxy-3-methylbutanoateC5H10O4Chemical structure of 2,3-dihydroxy-3-methylbutanoate1756-18-9
Average134.1305Da
Monoisotopic134.0579088Da
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm00002593alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da
BASm00002603alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da

Displaying 1–10 of 4785 metabolites

Health Effects

Health ConditionRelationReference
Gi diseaseCausesPMC11149725
UtisCausesPMC11434687
Colorectal cancerCausesPMC12198655
Pyogenic liver abscessesCausesPMC12392612
UtiCausesPMC13014981
ColibacillosisCausesPMC13255289
Enteric infectionsCausesPMC13255289
Foodborne infectionsCausesPMC13255289
Clinical mastitisCausesPMC13293316
DiarrheaCausesPMC3035056

Displaying health effects 1 – 10 of 103 in total