Escherichia coli strain FWSEC0400

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Escherichia

Description

Escherichia coli strain FWSEC0400 is a Gram-negative, rod-shaped bacterium primarily associated with various hosts, including Homo sapiens and domesticated animals such as Gallus gallus and Bos taurus. This strain exhibits a facultative anaerobic metabolism, allowing it to thrive in both aerobic and anaerobic environments. The optimal growth temperature is 37°C, placing it within the mesophilic temperature range. The cellular arrangement of FWSEC0400 is characterized by singles and pairs, and it possesses flagella, indicating motility. It has a unique configuration with one replicon and two membranes, typical of Gram-negative bacteria. The strain is also noted for its free-living biotic relationship, allowing it to inhabit diverse ecological niches. Clinically, FWSEC0400 is linked to a range of health effects, particularly in humans. It is associated with urinary tract infections (UTIs), gastrointestinal infections, peritonitis, and severe conditions like septicemia and hemolytic uremic syndrome (HUS). Other health effects include neonatal meningitis, diarrhea, and complications leading to chronic conditions such as colorectal cancer and renal failure. The extensive host range of FWSEC0400, including various mammals, birds, and even plants, highlights its ecological versatility and potential for transmission between species. Its pathogenicity in humans, coupled with its ability to inhabit a wide array of environments, underscores the importance of monitoring E. coli strains like FWSEC0400 in public health and environmental microbiology.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusEscherichia
SpeciesEscherichia coli
Strainstrain FWSEC0400

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Escherichia coli strain FWSEC0400
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Bos taurus
Cell arrangementPairs - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Escherichia coli strain FWSEC0400 FWSEC0400_contig00128, whole

Gene Summary

Adenine Count

1200367 bp

Thymine Count

1210061 bp

Guanine Count

1224043 bp

Cytosine Count

1230474 bp

Genome Length

4874470 bp

Protein-coding Genes

4433 genes

Non-Coding Genes

213 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
low-specificity l-threonine aldolaseC9175_12645Not AvailablePositive2637808 - 263880936487.8
sdr family oxidoreductaseC9175_12650Not AvailablePositive2638820 - 264025053710.1
nad(p)-dependent oxidoreductaseC9175_12655Not AvailablePositive2640349 - 264136238087.9
n-acetylmuramoyl-l-alanine amidaseC9175_12660Not AvailableNegative2641359 - 264218931074.1
heavy metal-binding domain-containing proteinC9175_12665Not AvailableNegative2642186 - 264250911437.7
lipoproteinC9175_12670Not AvailablePositive2642635 - 264315018992.4
arginine abc transporter atp-binding protein artpC9175_12675Not AvailablePositive2643368 - 264409627023.7
arginine abc transporter substrate-binding proteinC9175_12680Not AvailablePositive2644114 - 264484526931.0
arginine abc transporter permease artqC9175_12685Not AvailablePositive2644852 - 264556826218.7
arginine abc transporter permease artmC9175_12690Not AvailablePositive2645568 - 264623624915.3

Displaying genes 2641 – 2650 of 4663 in total

Metabolites

4785 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000173(R)-3-Hydroxybutyric acidC4H8O3Chemical structure of (R)-3-Hydroxybutyric acid625-72-3
Average104.0473Da
Monoisotopic104.047344122Da
BASm0000217alpha-ribazoleC14H18N2O4Chemical structure of alpha-ribazoleNot available
Average278.3037Da
Monoisotopic278.126657074Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm0000238(R)-3-phenyllactateC9H9O3Chemical structure of (R)-3-phenyllactateNot available
Average165.169Da
Monoisotopic165.05571773Da
BASm00002482,3-dihydroxy-3-methylbutanoateC5H10O4Chemical structure of 2,3-dihydroxy-3-methylbutanoate1756-18-9
Average134.1305Da
Monoisotopic134.0579088Da
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm00002593alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da
BASm00002603alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da

Displaying 1–10 of 4785 metabolites

Health Effects

Health ConditionRelationReference
Gi diseaseCausesPMC11149725
UtisCausesPMC11434687
Colorectal cancerCausesPMC12198655
Pyogenic liver abscessesCausesPMC12392612
UtiCausesPMC13014981
ColibacillosisCausesPMC13255289
Enteric infectionsCausesPMC13255289
Foodborne infectionsCausesPMC13255289
Clinical mastitisCausesPMC13293316
DiarrheaCausesPMC3035056

Displaying health effects 1 – 10 of 103 in total