Escherichia coli strain FWSEC0400

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Escherichia

Description

Escherichia coli strain FWSEC0400 is a Gram-negative, rod-shaped bacterium primarily associated with various hosts, including Homo sapiens and domesticated animals such as Gallus gallus and Bos taurus. This strain exhibits a facultative anaerobic metabolism, allowing it to thrive in both aerobic and anaerobic environments. The optimal growth temperature is 37°C, placing it within the mesophilic temperature range. The cellular arrangement of FWSEC0400 is characterized by singles and pairs, and it possesses flagella, indicating motility. It has a unique configuration with one replicon and two membranes, typical of Gram-negative bacteria. The strain is also noted for its free-living biotic relationship, allowing it to inhabit diverse ecological niches. Clinically, FWSEC0400 is linked to a range of health effects, particularly in humans. It is associated with urinary tract infections (UTIs), gastrointestinal infections, peritonitis, and severe conditions like septicemia and hemolytic uremic syndrome (HUS). Other health effects include neonatal meningitis, diarrhea, and complications leading to chronic conditions such as colorectal cancer and renal failure. The extensive host range of FWSEC0400, including various mammals, birds, and even plants, highlights its ecological versatility and potential for transmission between species. Its pathogenicity in humans, coupled with its ability to inhabit a wide array of environments, underscores the importance of monitoring E. coli strains like FWSEC0400 in public health and environmental microbiology.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusEscherichia
SpeciesEscherichia coli
Strainstrain FWSEC0400

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Escherichia coli strain FWSEC0400
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Bos taurus
Cell arrangementPairs - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Escherichia coli strain FWSEC0400 FWSEC0400_contig00128, whole

Gene Summary

Adenine Count

1200367 bp

Thymine Count

1210061 bp

Guanine Count

1224043 bp

Cytosine Count

1230474 bp

Genome Length

4874470 bp

Protein-coding Genes

4433 genes

Non-Coding Genes

213 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
heat-shock protein hspqC9175_05320Not AvailableNegative1159663 - 115998011779.9
ribosomal rna large subunit methyltransferase iC9175_05325Not AvailableNegative1160038 - 116122844359.5
acylphosphataseC9175_05330Not AvailablePositive1161323 - 116160110300.3
sulfurtransferase tuseC9175_05335Not AvailableNegative1161598 - 116192712411.0
bax inhibitor proteinC9175_05340Not AvailableNegative1162018 - 116267723364.3
Trna-serNot AvailableNot AvailablePositive1162884 - 1162971Not Available
hydrogenase-1 small chainC9175_05350Not AvailablePositive1163398 - 116451640683.6
hydrogenase-1 large chainC9175_05355Not AvailablePositive1164513 - 116630666257.0
ni/fe-hydrogenase b-type cytochrome subunitC9175_05360Not AvailablePositive1166325 - 116703227598.8
hydrogenase 1 maturation proteaseC9175_05365Not AvailablePositive1167029 - 116761621547.7

Displaying genes 1251 – 1260 of 4663 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

4785 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000173(R)-3-Hydroxybutyric acidC4H8O3Chemical structure of (R)-3-Hydroxybutyric acid625-72-3
Average104.0473Da
Monoisotopic104.047344122Da
BASm0000217alpha-ribazoleC14H18N2O4Chemical structure of alpha-ribazoleNot available
Average278.3037Da
Monoisotopic278.126657074Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm0000238(R)-3-phenyllactateC9H9O3Chemical structure of (R)-3-phenyllactateNot available
Average165.169Da
Monoisotopic165.05571773Da
BASm00002482,3-dihydroxy-3-methylbutanoateC5H10O4Chemical structure of 2,3-dihydroxy-3-methylbutanoate1756-18-9
Average134.1305Da
Monoisotopic134.0579088Da
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm00002593alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da
BASm00002603alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da

Displaying 1–10 of 4785 metabolites

Health Effects

Health ConditionRelationReference
Gi diseaseCausesPMC11149725
UtisCausesPMC11434687
Colorectal cancerCausesPMC12198655
Pyogenic liver abscessesCausesPMC12392612
UtiCausesPMC13014981
ColibacillosisCausesPMC13255289
Enteric infectionsCausesPMC13255289
Foodborne infectionsCausesPMC13255289
Clinical mastitisCausesPMC13293316
DiarrheaCausesPMC3035056

Displaying health effects 1 – 10 of 103 in total