Escherichia coli strain FWSEC0398

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Escherichia

Description

Escherichia coli strain FWSEC0398 is a Gram-negative, rod-shaped bacterium characterized by its facultative anaerobic metabolism and motility, facilitated by the presence of flagella. This strain is adapted to host-associated environments, thriving optimally at 37°C, which is typical for mesophilic organisms. The bacterium has a biotic relationship as a free-living organism, allowing it to inhabit various hosts, including Homo sapiens, Gallus gallus, Bos taurus, and numerous other vertebrates and invertebrates. FWSEC0398 is associated with a range of health effects, notably urinary tract infections (UTIs), gastrointestinal infections, and neonatal meningitis. It can cause severe conditions such as hemorrhagic colitis, hemolytic uremic syndrome (HUS), and septicemia. In particular, its pathogenicity in humans highlights its role in both community-acquired and nosocomial infections, contributing to significant health burdens. The strain's versatility in host associations, including interactions with mammals, birds, and even invertebrates like Apis mellifera, suggests a complex ecological role in microbial communities. Furthermore, the diverse array of diseases linked to FWSEC0398 underscores its potential impact on public health, particularly through foodborne infections and opportunistic infections in vulnerable populations. Understanding the ecological dynamics of E. coli strain FWSEC0398 can provide insights into its transmission pathways and the management of associated health risks.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusEscherichia
SpeciesEscherichia coli
Strainstrain FWSEC0398

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Escherichia coli strain FWSEC0398
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Bos taurus
Cell arrangementPairs - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Escherichia coli strain FWSEC0398 plasmid unnamed6

Gene Summary

Adenine Count

Not Available

Thymine Count

Not Available

Guanine Count

Not Available

Cytosine Count

Not Available

Genome Length

Not Available

Protein-coding Genes

4342 genes

Non-Coding Genes

200 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
Hypothetical proteinC9173_12935Not AvailableNegative2725395 - 272610827275.3
Antirestriction proteinC9173_12940Not AvailableNegative2726163 - 27262342618.3
hypothetical proteinC9173_12945Not AvailableNegative2726204 - 27262602157.51
NunC9173_12950Not AvailableNegative2726462 - 272680013234.8
Antitermination protein nC9173_12955Not AvailableNegative2726769 - 272710712914.6
Hypothetical proteinC9173_12960Not AvailablePositive2727441 - 27276627913.82
Transcription regulatory protein prtrC9173_12965Not AvailableNegative2727815 - 272852225886.9
Regulatory protein croC9173_12970Not AvailablePositive2728633 - 27288578125.88
Cii proteinC9173_12975Not AvailablePositive2728973 - 272926911017.4
Hypothetical proteinC9173_12980Not AvailablePositive2729284 - 27295028163.43

Displaying genes 41 – 50 of 4545 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

4785 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000173(R)-3-Hydroxybutyric acidC4H8O3Chemical structure of (R)-3-Hydroxybutyric acid625-72-3
Average104.0473Da
Monoisotopic104.047344122Da
BASm0000217alpha-ribazoleC14H18N2O4Chemical structure of alpha-ribazoleNot available
Average278.3037Da
Monoisotopic278.126657074Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm0000238(R)-3-phenyllactateC9H9O3Chemical structure of (R)-3-phenyllactateNot available
Average165.169Da
Monoisotopic165.05571773Da
BASm00002482,3-dihydroxy-3-methylbutanoateC5H10O4Chemical structure of 2,3-dihydroxy-3-methylbutanoate1756-18-9
Average134.1305Da
Monoisotopic134.0579088Da
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm00002593alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da
BASm00002603alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da

Displaying 1–10 of 4785 metabolites

Health Effects

Health ConditionRelationReference
Gi diseaseCausesPMC11149725
UtisCausesPMC11434687
Colorectal cancerCausesPMC12198655
Pyogenic liver abscessesCausesPMC12392612
UtiCausesPMC13014981
ColibacillosisCausesPMC13255289
Enteric infectionsCausesPMC13255289
Foodborne infectionsCausesPMC13255289
Clinical mastitisCausesPMC13293316
DiarrheaCausesPMC3035056

Displaying health effects 1 – 10 of 103 in total