Escherichia coli strain FWSEC0398

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Escherichia

Description

Escherichia coli strain FWSEC0398 is a Gram-negative, rod-shaped bacterium characterized by its facultative anaerobic metabolism and motility, facilitated by the presence of flagella. This strain is adapted to host-associated environments, thriving optimally at 37°C, which is typical for mesophilic organisms. The bacterium has a biotic relationship as a free-living organism, allowing it to inhabit various hosts, including Homo sapiens, Gallus gallus, Bos taurus, and numerous other vertebrates and invertebrates. FWSEC0398 is associated with a range of health effects, notably urinary tract infections (UTIs), gastrointestinal infections, and neonatal meningitis. It can cause severe conditions such as hemorrhagic colitis, hemolytic uremic syndrome (HUS), and septicemia. In particular, its pathogenicity in humans highlights its role in both community-acquired and nosocomial infections, contributing to significant health burdens. The strain's versatility in host associations, including interactions with mammals, birds, and even invertebrates like Apis mellifera, suggests a complex ecological role in microbial communities. Furthermore, the diverse array of diseases linked to FWSEC0398 underscores its potential impact on public health, particularly through foodborne infections and opportunistic infections in vulnerable populations. Understanding the ecological dynamics of E. coli strain FWSEC0398 can provide insights into its transmission pathways and the management of associated health risks.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusEscherichia
SpeciesEscherichia coli
Strainstrain FWSEC0398

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Escherichia coli strain FWSEC0398
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Bos taurus
Cell arrangementPairs - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Escherichia coli strain FWSEC0398 plasmid unnamed6

Gene Summary

Adenine Count

Not Available

Thymine Count

Not Available

Guanine Count

Not Available

Cytosine Count

Not Available

Genome Length

Not Available

Protein-coding Genes

4342 genes

Non-Coding Genes

200 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
endonuclease-1C9173_10305Not AvailablePositive2188637 - 218934426724.5
ribosomal rna small subunit methyltransferase eC9173_10310Not AvailablePositive2189424 - 219015526979.7
glutathione synthetaseC9173_10315Not AvailablePositive2190168 - 219111835563.0
yqge/algh family proteinC9173_10320Not AvailablePositive2191227 - 219179020687.1
holliday junction resolvase ruvxC9173_10325Not AvailablePositive2191790 - 219220615173.2
yggs family pyridoxal phosphate-dependent enzymeC9173_10335Not AvailablePositive2193385 - 219408925788.9
yggt family proteinC9173_10340Not AvailablePositive2194107 - 219467321168.5
yggu family proteinC9173_10345Not AvailablePositive2194670 - 219496010429.8
non-canonical purine ntp pyrophosphataseC9173_10350Not AvailablePositive2194968 - 219556120979.9
radical sam family heme chaperone hemwC9173_10355Not AvailablePositive2195554 - 219669042574.6

Displaying genes 2151 – 2160 of 4545 in total

Metabolites

4785 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000173(R)-3-Hydroxybutyric acidC4H8O3Chemical structure of (R)-3-Hydroxybutyric acid625-72-3
Average104.0473Da
Monoisotopic104.047344122Da
BASm0000217alpha-ribazoleC14H18N2O4Chemical structure of alpha-ribazoleNot available
Average278.3037Da
Monoisotopic278.126657074Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm0000238(R)-3-phenyllactateC9H9O3Chemical structure of (R)-3-phenyllactateNot available
Average165.169Da
Monoisotopic165.05571773Da
BASm00002482,3-dihydroxy-3-methylbutanoateC5H10O4Chemical structure of 2,3-dihydroxy-3-methylbutanoate1756-18-9
Average134.1305Da
Monoisotopic134.0579088Da
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm00002593alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da
BASm00002603alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da

Displaying 1–10 of 4785 metabolites

Health Effects

Health ConditionRelationReference
Gi diseaseCausesPMC11149725
UtisCausesPMC11434687
Colorectal cancerCausesPMC12198655
Pyogenic liver abscessesCausesPMC12392612
UtiCausesPMC13014981
ColibacillosisCausesPMC13255289
Enteric infectionsCausesPMC13255289
Foodborne infectionsCausesPMC13255289
Clinical mastitisCausesPMC13293316
DiarrheaCausesPMC3035056

Displaying health effects 1 – 10 of 103 in total