Escherichia coli strain FWSEC0394

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Escherichia

Description

Escherichia coli strain FWSEC0394 is a Gram-negative, rod-shaped bacterium that exhibits mobility due to the presence of flagella. This strain is classified as a facultative anaerobe, allowing it to thrive in both aerobic and anaerobic environments. The optimal growth temperature for FWSEC0394 is 37°C, placing it within the mesophilic temperature range. It is characterized by a cell arrangement of pairs and singles, and it possesses a single replicon and a double membrane structure. FWSEC0394 is primarily host-associated, with a diverse range of hosts including Homo sapiens, Gallus gallus, Bos taurus, and various other vertebrates and invertebrates. This indicates a broad ecological niche, allowing it to survive in multiple environments, from livestock to human hosts. Health effects associated with this strain are significant, as it is linked to various diseases, including urinary tract infections (UTIs), gastrointestinal infections, neonatal meningitis, and even severe conditions such as hemolytic uremic syndrome (HUS). The strain's pathogenicity primarily affects humans, but it also poses risks to other animals, highlighting its potential impact on both public health and veterinary medicine. The extensive range of health effects and host associations underscores the ecological importance of FWSEC0394, suggesting that it plays a complex role in both environmental and clinical settings. Understanding its behavior and pathogenicity can provide insights into managing infections and preventing disease spread among various species.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusEscherichia
SpeciesEscherichia coli
Strainstrain FWSEC0394

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Escherichia coli strain FWSEC0394
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Bos taurus
Cell arrangementPairs - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Escherichia coli strain FWSEC0394 plasmid unnamed3

Gene Summary

Adenine Count

1307856 bp

Thymine Count

1305726 bp

Guanine Count

1305776 bp

Cytosine Count

1334227 bp

Genome Length

5261935 bp

Protein-coding Genes

4823 genes

Non-Coding Genes

324 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
type iii secretion system lee grla-binding negative regulator grlrC9169_13115Not AvailablePositive2808165 - 280853613929.9
type iii secretion system lee transcriptional regulator grlaC9169_13120Not AvailablePositive2808591 - 280900416085.4
type iii secretion system lee chaperone cesdC9169_13125Not AvailableNegative2809388 - 280984317503.7
type iii secretion system lee outer membrane ring protein esccC9169_13130Not AvailableNegative2809857 - 281139556201.9
type iii secretion system lee switch protein sepdC9169_13135Not AvailableNegative2811395 - 281185017562.0
type iii secretion system lee inner membrane ring protein escjC9169_13140Not AvailableNegative2811856 - 281242820758.1
esci/ysci/hrpb family type iii secretion system inner rod proteinC9169_13145Not AvailableNegative2812431 - 281280813272.8
type iii secretion system lee cytoprotective effector espzC9169_13150Not AvailableNegative2812892 - 28131919656.61
type iii secretion system lee chaperone ceslC9169_13155Not AvailablePositive2813376 - 281372913942.8
type iii secretion system lee export apparatus protein escvC9169_13160Not AvailablePositive2813726 - 281575375101.7

Displaying genes 2851 – 2860 of 5151 in total

Metabolites

4785 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000173(R)-3-Hydroxybutyric acidC4H8O3Chemical structure of (R)-3-Hydroxybutyric acid625-72-3
Average104.0473Da
Monoisotopic104.047344122Da
BASm0000217alpha-ribazoleC14H18N2O4Chemical structure of alpha-ribazoleNot available
Average278.3037Da
Monoisotopic278.126657074Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm0000238(R)-3-phenyllactateC9H9O3Chemical structure of (R)-3-phenyllactateNot available
Average165.169Da
Monoisotopic165.05571773Da
BASm00002482,3-dihydroxy-3-methylbutanoateC5H10O4Chemical structure of 2,3-dihydroxy-3-methylbutanoate1756-18-9
Average134.1305Da
Monoisotopic134.0579088Da
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm00002593alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da
BASm00002603alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da

Displaying 1–10 of 4785 metabolites

Health Effects

Health ConditionRelationReference
Gi diseaseCausesPMC11149725
UtisCausesPMC11434687
Colorectal cancerCausesPMC12198655
Pyogenic liver abscessesCausesPMC12392612
UtiCausesPMC13014981
ColibacillosisCausesPMC13255289
Enteric infectionsCausesPMC13255289
Foodborne infectionsCausesPMC13255289
Clinical mastitisCausesPMC13293316
DiarrheaCausesPMC3035056

Displaying health effects 1 – 10 of 103 in total