Escherichia coli strain FWSEC0379

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Escherichia

Description

Escherichia coli strain FWSEC0379 is a Gram-negative, rod-shaped bacterium that is classified as a facultative anaerobe. It exhibits mobility due to the presence of flagella and typically arranges itself in pairs or singles. This strain thrives optimally at a temperature of 37°C, fitting within the mesophilic temperature range. It possesses a single replicon and is characterized by a double membrane structure. FWSEC0379 is notably associated with various hosts, including Homo sapiens (humans), Gallus gallus (chickens), Bos taurus (cattle), and several other vertebrates and invertebrates, such as Apis mellifera (honeybees) and Solanum lycopersicum (tomatoes). This diverse host range indicates the strain's ecological flexibility and its potential to interact with multiple biological systems. Health effects attributed to FWSEC0379 are significant, with implications for both human and animal health. The strain is associated with a variety of infections, including urinary tract infections (UTIs), gastrointestinal infections, and neonatal meningitis. Its pathogenicity in humans is of particular concern, linked to conditions such as hemorrhagic colitis and hemolytic uremic syndrome (HUS), which are serious health threats. The strain's free-living biotic relationship suggests that it can adapt to various environments, which may contribute to its ability to persist and spread among different hosts. This adaptability, combined with its pathogenic potential, highlights the importance of monitoring E. coli strains like FWSEC0379 in both clinical and ecological contexts to understand their role in health and disease dynamics.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusEscherichia
SpeciesEscherichia coli
Strainstrain FWSEC0379

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Escherichia coli strain FWSEC0379
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Bos taurus
Cell arrangementPairs - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Escherichia coli strain FWSEC0379 plasmid unnamed5

Gene Summary

Adenine Count

1337578 bp

Thymine Count

1331621 bp

Guanine Count

1347838 bp

Cytosine Count

1352021 bp

Genome Length

5382183 bp

Protein-coding Genes

4937 genes

Non-Coding Genes

453 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
Gene 2 proteinC9155_05400Not AvailableNegative1113139 - 111455153056.1
Terminase small subunitC9155_05405Not AvailableNegative1114548 - 111497315770.8
Duf2560 family proteinC9155_05410Not AvailableNegative1115053 - 11152959012.78
Hypothetical proteinC9155_05415Not AvailableNegative1115399 - 111577013644.2
Rha family transcriptional regulatorC9155_05420Not AvailableNegative1116054 - 111657220198.6
Rz lysis proteinC9155_05425Not AvailableNegative1116778 - 111721516184.3
EndopeptidaseC9155_05430Not AvailableNegative1117212 - 111768817854.2
HolinC9155_05435Not AvailableNegative1117672 - 111799511422.0
AttrNot AvailableNot AvailablePositive1118159 - 1118170Not Available
hypothetical proteinC9155_05440Not AvailablePositive1118483 - 11187018086.93

Displaying genes 71 – 80 of 5394 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

4785 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000173(R)-3-Hydroxybutyric acidC4H8O3Chemical structure of (R)-3-Hydroxybutyric acid625-72-3
Average104.0473Da
Monoisotopic104.047344122Da
BASm0000217alpha-ribazoleC14H18N2O4Chemical structure of alpha-ribazoleNot available
Average278.3037Da
Monoisotopic278.126657074Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm0000238(R)-3-phenyllactateC9H9O3Chemical structure of (R)-3-phenyllactateNot available
Average165.169Da
Monoisotopic165.05571773Da
BASm00002482,3-dihydroxy-3-methylbutanoateC5H10O4Chemical structure of 2,3-dihydroxy-3-methylbutanoate1756-18-9
Average134.1305Da
Monoisotopic134.0579088Da
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm00002593alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da
BASm00002603alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da

Displaying 1–10 of 4785 metabolites

Health Effects

Health ConditionRelationReference
Gi diseaseCausesPMC11149725
UtisCausesPMC11434687
Colorectal cancerCausesPMC12198655
Pyogenic liver abscessesCausesPMC12392612
UtiCausesPMC13014981
ColibacillosisCausesPMC13255289
Enteric infectionsCausesPMC13255289
Foodborne infectionsCausesPMC13255289
Clinical mastitisCausesPMC13293316
DiarrheaCausesPMC3035056

Displaying health effects 1 – 10 of 103 in total