Escherichia coli strain FWSEC0379

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Escherichia

Description

Escherichia coli strain FWSEC0379 is a Gram-negative, rod-shaped bacterium that is classified as a facultative anaerobe. It exhibits mobility due to the presence of flagella and typically arranges itself in pairs or singles. This strain thrives optimally at a temperature of 37°C, fitting within the mesophilic temperature range. It possesses a single replicon and is characterized by a double membrane structure. FWSEC0379 is notably associated with various hosts, including Homo sapiens (humans), Gallus gallus (chickens), Bos taurus (cattle), and several other vertebrates and invertebrates, such as Apis mellifera (honeybees) and Solanum lycopersicum (tomatoes). This diverse host range indicates the strain's ecological flexibility and its potential to interact with multiple biological systems. Health effects attributed to FWSEC0379 are significant, with implications for both human and animal health. The strain is associated with a variety of infections, including urinary tract infections (UTIs), gastrointestinal infections, and neonatal meningitis. Its pathogenicity in humans is of particular concern, linked to conditions such as hemorrhagic colitis and hemolytic uremic syndrome (HUS), which are serious health threats. The strain's free-living biotic relationship suggests that it can adapt to various environments, which may contribute to its ability to persist and spread among different hosts. This adaptability, combined with its pathogenic potential, highlights the importance of monitoring E. coli strains like FWSEC0379 in both clinical and ecological contexts to understand their role in health and disease dynamics.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusEscherichia
SpeciesEscherichia coli
Strainstrain FWSEC0379

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Escherichia coli strain FWSEC0379
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Bos taurus
Cell arrangementPairs - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Escherichia coli strain FWSEC0379 plasmid unnamed5

Gene Summary

Adenine Count

1337578 bp

Thymine Count

1331621 bp

Guanine Count

1347838 bp

Cytosine Count

1352021 bp

Genome Length

5382183 bp

Protein-coding Genes

4937 genes

Non-Coding Genes

453 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
flagellar basal body rod protein flgbC9155_16890Not AvailablePositive3449468 - 344980312429.7
flagellar basal body rod protein flgcC9155_16895Not AvailablePositive3449806 - 345023715367.0
flagellar hook capping proteinC9155_16900Not AvailablePositive3450237 - 345095024674.2
flagellar basal body protein flaeC9155_16905Not AvailablePositive3450974 - 345217641865.6
flagellar basal body rod protein flgfC9155_16910Not AvailablePositive3452176 - 345291325915.3
flagellar basal-body rod protein flggC9155_16915Not AvailablePositive3452992 - 345377727507.3
flagellar basal body l-ring protein flghC9155_16920Not AvailablePositive3453860 - 345452524001.1
flagellar basal body p-ring protein flgiC9155_16925Not AvailablePositive3454540 - 345564037614.9
rod-binding proteinC9155_16930Not AvailablePositive3455640 - 345593911020.3
flagellar hook-associated protein flgkC9155_16935Not AvailablePositive3456193 - 345756948258.9

Displaying genes 3581 – 3590 of 5394 in total

Metabolites

4785 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000173(R)-3-Hydroxybutyric acidC4H8O3Chemical structure of (R)-3-Hydroxybutyric acid625-72-3
Average104.0473Da
Monoisotopic104.047344122Da
BASm0000217alpha-ribazoleC14H18N2O4Chemical structure of alpha-ribazoleNot available
Average278.3037Da
Monoisotopic278.126657074Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm0000238(R)-3-phenyllactateC9H9O3Chemical structure of (R)-3-phenyllactateNot available
Average165.169Da
Monoisotopic165.05571773Da
BASm00002482,3-dihydroxy-3-methylbutanoateC5H10O4Chemical structure of 2,3-dihydroxy-3-methylbutanoate1756-18-9
Average134.1305Da
Monoisotopic134.0579088Da
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm00002593alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da
BASm00002603alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da

Displaying 1–10 of 4785 metabolites

Health Effects

Health ConditionRelationReference
Gi diseaseCausesPMC11149725
UtisCausesPMC11434687
Colorectal cancerCausesPMC12198655
Pyogenic liver abscessesCausesPMC12392612
UtiCausesPMC13014981
ColibacillosisCausesPMC13255289
Enteric infectionsCausesPMC13255289
Foodborne infectionsCausesPMC13255289
Clinical mastitisCausesPMC13293316
DiarrheaCausesPMC3035056

Displaying health effects 1 – 10 of 103 in total