Escherichia coli strain FWSEC0378

Escherichia coli strain FWSEC0378 is a Gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic metabolism, allowing it to thrive in both aerobic and anaerobic environments. This strain is motile, possessing flagella, and typically arranges itself in pairs or as single cells. It is classified as mesophilic, with an optimal growth temperature of 37°C. FWSEC0378 is host-associated and demonstrates a significant biotic relationship, being free-living. Its host range is extensive, including various species such as Homo sapiens, Gallus gallus, Bos taurus, and multiple other vertebrates and invertebrates, highlighting its adaptability and potential for cross-species transmission. The pathogenicity of this strain is notable, as it is linked to a wide range of health effects in humans and animals. It is commonly associated with urinary tract infections (UTIs), gastrointestinal infections, and severe conditions such as neonatal meningitis and hemolytic uremic syndrome (HUS). The strain's involvement in foodborne infections and its potential to cause severe gastrointestinal diseases underscores its significance in public health. The diverse array of hosts and the associated health effects signify the ecological versatility of E. coli strain FWSEC0378. Its ability to infect numerous species, including humans and livestock, suggests that it plays a complex role in both the microbiome and the epidemiology of infectious diseases, emphasizing the need for ongoing surveillance and research to understand its impact on health and disease across different organisms.