Escherichia coli strain FWSEC0374

Escherichia coli strain FWSEC0374 is a Gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic metabolism. It is characterized by its mobility, attributed to the presence of flagella, and typically exists in various arrangements, including singles and pairs. This strain thrives optimally at 37°C, falling within the mesophilic temperature range. FWSEC0374 is associated with a diverse array of hosts, including Homo sapiens (humans), Gallus gallus (chickens), Bos taurus (cattle), and various other vertebrates and invertebrates. Its free-living biotic relationship allows it to inhabit multiple environments, including those associated with animals and plants like Solanum lycopersicum (tomato) and Brassica oleracea var. italica (broccoli). The strain is notable for its pathogenic potential, being linked to a wide range of health effects, particularly in humans. It has been implicated in urinary tract infections (UTIs), gastrointestinal infections, peritonitis, and even severe conditions such as hemolytic uremic syndrome (HUS) and neonatal meningitis. The presence of FWSEC0374 in diverse hosts suggests its ecological versatility and potential for transmission across species, raising concerns about food safety and public health. Understanding the ecological roles and pathogenic mechanisms of E. coli strains like FWSEC0374 is critical for managing infections and preventing outbreaks associated with this significant pathogen.