Escherichia coli strain FWSEC0370

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Escherichia

Description

Escherichia coli strain FWSEC0370 is a Gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic metabolism. This strain is motile and possesses flagella, allowing it to move in various environments. It is typically found in host-associated habitats and is classified as free-living. The optimal temperature for growth is 37°C, placing it within a mesophilic temperature range. FWSEC0370 has a single replicon and is characterized by a double membrane structure. It has a broad range of hosts, including Homo sapiens, various livestock such as Bos taurus and Gallus gallus, as well as several other vertebrates and invertebrates, indicating its ecological versatility. Clinically, this strain is known to be pathogenic in humans and is associated with numerous health effects, particularly urinary tract infections (UTIs), gastrointestinal infections, and severe conditions such as septicemia and hemolytic uremic syndrome (HUS). The presence of FWSEC0370 in diverse hosts and its capability to cause significant health issues underscore its role in both environmental and clinical microbiology. The versatility of E. coli strain FWSEC0370 in colonizing various hosts, combined with its pathogenic potential, highlights the importance of monitoring such strains in both healthcare settings and agricultural environments. Understanding its ecological relationships and health impacts can provide valuable insights into disease prevention and management strategies.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusEscherichia
SpeciesEscherichia coli
Strainstrain FWSEC0370

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Escherichia coli strain FWSEC0370
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Bos taurus
Cell arrangementPairs - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Escherichia coli strain FWSEC0370


Gene Summary

Adenine Count

1319185 bp

Thymine Count

1323180 bp

Guanine Count

1334001 bp

Cytosine Count

1347843 bp

Genome Length

5336204 bp

Protein-coding Genes

4792 genes

Non-Coding Genes

478 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
malate synthase aC9146_18015Not AvailablePositive3649008 - 365060960300.0
isocitrate lyaseC9146_18020Not AvailablePositive3650639 - 365194347524.1
bifunctional isocitrate dehydrogenase kinase/phosphataseC9146_18025Not AvailablePositive3652126 - 365386267674.3
shet2/espl2 family type iii secretion system effector toxinC9146_18030Not AvailableNegative3653831 - 365601782691.9
glyoxylate bypass operon transcriptional repressor iclrC9146_18035Not AvailableNegative3656334 - 365715829760.2
methionine synthaseC9146_18040Not AvailablePositive3657358 - 3661041136076.0
na/pi cotransporter family proteinC9146_18045Not AvailablePositive3661261 - 366289259451.6
dipeptidase pepeC9146_18050Not AvailableNegative3662983 - 366367224571.7
23s rrna pseudouridine(2604) synthase rlufC9146_18055Not AvailablePositive3663884 - 366475632422.4
duf3811 domain-containing proteinC9146_18060Not AvailableNegative3664889 - 366516110546.7

Displaying genes 3681 – 3690 of 5274 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

4785 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000173(R)-3-Hydroxybutyric acidC4H8O3Chemical structure of (R)-3-Hydroxybutyric acid625-72-3
Average104.0473Da
Monoisotopic104.047344122Da
BASm0000217alpha-ribazoleC14H18N2O4Chemical structure of alpha-ribazoleNot available
Average278.3037Da
Monoisotopic278.126657074Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm0000238(R)-3-phenyllactateC9H9O3Chemical structure of (R)-3-phenyllactateNot available
Average165.169Da
Monoisotopic165.05571773Da
BASm00002482,3-dihydroxy-3-methylbutanoateC5H10O4Chemical structure of 2,3-dihydroxy-3-methylbutanoate1756-18-9
Average134.1305Da
Monoisotopic134.0579088Da
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm00002593alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da
BASm00002603alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da

Displaying 1–10 of 4785 metabolites

Health Effects

Health ConditionRelationReference
Gi diseaseCausesPMC11149725
UtisCausesPMC11434687
Colorectal cancerCausesPMC12198655
Pyogenic liver abscessesCausesPMC12392612
UtiCausesPMC13014981
ColibacillosisCausesPMC13255289
Enteric infectionsCausesPMC13255289
Foodborne infectionsCausesPMC13255289
Clinical mastitisCausesPMC13293316
DiarrheaCausesPMC3035056

Displaying health effects 1 – 10 of 103 in total