Escherichia coli strain FWSEC0351

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Escherichia

Description

Escherichia coli strain FWSEC0351 is a Gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic lifestyle, allowing it to thrive in both aerobic and anaerobic environments. This strain is motile and possesses flagella, enabling movement. It is classified as mesophilic, with an optimal growth temperature of 37°C. FWSEC0351 is host-associated, demonstrating a free-living biotic relationship. It has a diverse range of hosts, including Homo sapiens (humans), various domestic animals such as Gallus gallus (chickens), Bos taurus (cattle), and Sus scrofa (pigs), as well as other vertebrates and invertebrates. This extensive host range suggests a significant ecological adaptability, allowing FWSEC0351 to inhabit multiple niches in both wild and domesticated environments. In terms of health implications, FWSEC0351 is associated with a variety of serious health issues in humans and other hosts, including urinary tract infections (UTIs), gastrointestinal infections, neonatal meningitis, and conditions such as hemolytic uremic syndrome (HUS). The strain's pathogenicity in humans underscores its role as a potential threat to public health, as it can lead to severe outcomes like renal failure and even death in vulnerable populations. The presence of FWSEC0351 in such a wide range of hosts, coupled with its pathogenic potential, highlights the ecological significance of this strain in the context of zoonotic diseases and foodborne infections. Understanding its behavior and interactions within different host species is crucial for managing its impact on health and for developing effective interventions to mitigate its pathogenic effects.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusEscherichia
SpeciesEscherichia coli
Strainstrain FWSEC0351

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Escherichia coli strain FWSEC0351
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Bos taurus
Cell arrangementPairs - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Escherichia coli strain FWSEC0351


Gene Summary

Adenine Count

1234397 bp

Thymine Count

1241417 bp

Guanine Count

1285780 bp

Cytosine Count

1260940 bp

Genome Length

5028369 bp

Protein-coding Genes

4462 genes

Non-Coding Genes

394 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
transcriptional regulatorC9127_07525Not AvailableNegative1548132 - 154885426822.1
fkbp-type peptidyl-prolyl cis-trans isomeraseC9127_07530Not AvailableNegative1549021 - 154983328913.4
protein slyxC9127_07535Not AvailablePositive1550054 - 15502728214.8
peptidylprolyl isomeraseC9127_07540Not AvailableNegative1550321 - 155091120854.1
yhev family putative metal-binding proteinC9127_07545Not AvailableNegative1551006 - 15512067599.17
glutathione-regulated potassium-efflux system protein kefbC9127_07550Not AvailableNegative1551216 - 155302166376.3
glutathione-regulated potassium-efflux system ancillary protein kefgC9127_07555Not AvailableNegative1553021 - 155357220827.9
abc transporter atp-binding proteinC9127_07560Not AvailablePositive1553703 - 155561671847.6
hydrolaseC9127_07565Not AvailablePositive1555616 - 155663838486.3
yheu family proteinC9127_07570Not AvailablePositive1556632 - 15568508470.04

Displaying genes 1721 – 1730 of 4857 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

4785 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000173(R)-3-Hydroxybutyric acidC4H8O3Chemical structure of (R)-3-Hydroxybutyric acid625-72-3
Average104.0473Da
Monoisotopic104.047344122Da
BASm0000217alpha-ribazoleC14H18N2O4Chemical structure of alpha-ribazoleNot available
Average278.3037Da
Monoisotopic278.126657074Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm0000238(R)-3-phenyllactateC9H9O3Chemical structure of (R)-3-phenyllactateNot available
Average165.169Da
Monoisotopic165.05571773Da
BASm00002482,3-dihydroxy-3-methylbutanoateC5H10O4Chemical structure of 2,3-dihydroxy-3-methylbutanoate1756-18-9
Average134.1305Da
Monoisotopic134.0579088Da
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm00002593alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da
BASm00002603alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da

Displaying 1–10 of 4785 metabolites

Health Effects

Health ConditionRelationReference
Gi diseaseCausesPMC11149725
UtisCausesPMC11434687
Colorectal cancerCausesPMC12198655
Pyogenic liver abscessesCausesPMC12392612
UtiCausesPMC13014981
ColibacillosisCausesPMC13255289
Enteric infectionsCausesPMC13255289
Foodborne infectionsCausesPMC13255289
Clinical mastitisCausesPMC13293316
DiarrheaCausesPMC3035056

Displaying health effects 1 – 10 of 103 in total