Escherichia coli strain FWSEC0347

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Escherichia

Description

Escherichia coli strain FWSEC0347 is a Gram-negative, rod-shaped bacterium that exhibits facultative anaerobic metabolism, allowing it to thrive in varying oxygen environments. This strain is motile, possessing flagella, and typically arranges in pairs or as single cells. It has an optimal growth temperature of 37°C and falls within the mesophilic temperature range. FWSEC0347 is associated with a variety of hosts, including Homo sapiens, Gallus gallus, Bos taurus, and several other vertebrates and invertebrates, indicating its broad ecological niches. This strain is free-living, suggesting it can survive independently outside of a host, although it is commonly found in host-associated environments. The health effects linked to FWSEC0347 are extensive, with implications for human health, particularly concerning urinary tract infections (UTIs), gastrointestinal infections, and more severe conditions such as neonatal meningitis and hemolytic uremic syndrome (HUS). These pathogenic traits underscore the strain's potential impact on both individual health and public health systems. The presence of E. coli strain FWSEC0347 in diverse hosts highlights its ecological adaptability and raises important considerations for food safety and disease management, particularly in agricultural and healthcare settings. The strain's ability to cause a range of infections necessitates ongoing surveillance and research to better understand its pathogenic mechanisms and to develop effective prevention strategies.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusEscherichia
SpeciesEscherichia coli
Strainstrain FWSEC0347

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Escherichia coli strain FWSEC0347
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Bos taurus
Cell arrangementPairs - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Escherichia coli strain FWSEC0347


Gene Summary

Adenine Count

1243280 bp

Thymine Count

1247611 bp

Guanine Count

1271407 bp

Cytosine Count

1294199 bp

Genome Length

5063882 bp

Protein-coding Genes

4602 genes

Non-Coding Genes

310 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
acyl-coa dehydrogenaseC9123_12275Not AvailablePositive2559982 - 256113343004.6
arac family transcriptional regulatorC9123_12280Not AvailableNegative2561176 - 256208734868.2
electron transfer flavoproteinC9123_12285Not AvailablePositive2562403 - 256316727457.9
electron transfer flavoprotein subunit alphaC9123_12290Not AvailablePositive2563187 - 256412533829.7
fad-dependent oxidoreductaseC9123_12295Not AvailablePositive2564181 - 256547045983.8
ferredoxin family proteinC9123_12300Not AvailablePositive2565467 - 256576010685.7
cyclohexanecarboxylate-coa ligaseC9123_12305Not AvailablePositive2565763 - 256746362766.9
phosphoenolpyruvate synthaseC9123_12310Not AvailableNegative2567520 - 256989887440.1
kinase/pyrophosphorylaseC9123_12315Not AvailablePositive2570231 - 257106431212.7
3-deoxy-7-phosphoheptulonate synthase arohC9123_12320Not AvailablePositive2571221 - 257226738751.3

Displaying genes 2631 – 2640 of 4914 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

315 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000217alpha-ribazoleC14H18N2O4Chemical structure of alpha-ribazoleNot available
Average278.3037Da
Monoisotopic278.126657074Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm00002593alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm0000377(S)-malateC4H4O5Chemical structure of (S)-malateNot available
Average132.0716Da
Monoisotopic132.005873238Da
BASm0000387(6R)-5,10-methylene-5,6,7,8-tetrahydrofolateC20H21N7O6Chemical structure of (6R)-5,10-methylene-5,6,7,8-tetrahydrofolateNot available
Average455.432Da
Monoisotopic455.1564286Da
BASm0000399(S)-allantoinC4H6N4O3Chemical structure of (S)-allantoin97-59-6
Average158.1154Da
Monoisotopic158.0439901Da
BASm0000401(S)-2-succinylamino-6-oxoheptanedioateC11H12NO8Chemical structure of (S)-2-succinylamino-6-oxoheptanedioateNot available
Average286.218Da
Monoisotopic286.0579371Da

Displaying 1–10 of 315 metabolites

Health Effects

Health ConditionRelationReference
Gi diseaseCausesPMC11149725
UtisCausesPMC11434687
Colorectal cancerCausesPMC12198655
Pyogenic liver abscessesCausesPMC12392612
UtiCausesPMC13014981
ColibacillosisCausesPMC13255289
Enteric infectionsCausesPMC13255289
Foodborne infectionsCausesPMC13255289
Clinical mastitisCausesPMC13293316
DiarrheaCausesPMC3035056

Displaying health effects 1 – 10 of 103 in total