Escherichia coli strain FWSEC0344

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Escherichia

Description

Escherichia coli strain FWSEC0344 is a Gram-negative, rod-shaped bacterium that displays mobility due to the presence of flagella. It is a facultative anaerobe, capable of thriving in both aerobic and anaerobic conditions, with an optimal growth temperature of 37°C, placing it firmly within the mesophilic temperature range. This strain is associated with a diverse range of hosts, including humans (Homo sapiens), various mammals such as cattle (Bos taurus), pigs (Sus scrofa), and species from other vertebrate classes like birds (Aves) and reptiles (Python regius), as well as plants such as Solanum lycopersicum and Brassica oleracea var. italica. FWSEC0344 exhibits a free-living biotic relationship, which suggests its ability to survive independently of a host organism while still being capable of causing infections. It is implicated in numerous health effects, including urinary tract infections (UTIs), gastrointestinal infections, neonatal meningitis, and various forms of colitis and sepsis. These pathogenic effects can lead to serious conditions such as hemolytic uremic syndrome (HUS), renal failure, and even neonatal mortality. The diverse range of hosts and the strain's pathogenic capabilities highlight its ecological versatility and potential for transmission between various species. This adaptability emphasizes the importance of monitoring E. coli strains like FWSEC0344 in both clinical and agricultural settings, as they can pose significant health risks not only to humans but also to animals and plants. Understanding the behaviors and interactions of such strains can provide insights into infection control and prevention strategies in public health and veterinary contexts.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusEscherichia
SpeciesEscherichia coli
Strainstrain FWSEC0344

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Escherichia coli strain FWSEC0344
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Bos taurus
Cell arrangementPairs - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Escherichia coli strain FWSEC0344


Gene Summary

Adenine Count

1242889 bp

Thymine Count

1234185 bp

Guanine Count

1255227 bp

Cytosine Count

1263439 bp

Genome Length

5006345 bp

Protein-coding Genes

4575 genes

Non-Coding Genes

237 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
type ii toxin-antitoxin system pard family antitoxinC9120_18805Not AvailablePositive3862299 - 386259511294.6
type ii toxin-antitoxin system rele/pare family toxinC9120_18810Not AvailablePositive3862597 - 386289311540.8
u32 family peptidaseC9120_18815Not AvailablePositive3862996 - 386435751226.1
hypothetical proteinC9120_18820Not AvailableNegative3864491 - 38647007886.79
hypothetical proteinC9120_18825Not AvailableNegative3864688 - 386500511465.9
lipid kinase yegsC9120_18830Not AvailablePositive3865419 - 386631831973.6
deor/glpr transcriptional regulatorC9120_18835Not AvailableNegative3866400 - 386717927946.9
galactitol-1-phosphate 5-dehydrogenaseC9120_18840Not AvailableNegative3867279 - 386824734965.3
pts galactitol transporter subunit iicC9120_18845Not AvailableNegative3868295 - 386965048460.2
pts galactitol transporter subunit iibC9120_18850Not AvailableNegative3869654 - 386993810208.7

Displaying genes 3741 – 3750 of 4838 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

4785 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000173(R)-3-Hydroxybutyric acidC4H8O3Chemical structure of (R)-3-Hydroxybutyric acid625-72-3
Average104.0473Da
Monoisotopic104.047344122Da
BASm0000217alpha-ribazoleC14H18N2O4Chemical structure of alpha-ribazoleNot available
Average278.3037Da
Monoisotopic278.126657074Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm0000238(R)-3-phenyllactateC9H9O3Chemical structure of (R)-3-phenyllactateNot available
Average165.169Da
Monoisotopic165.05571773Da
BASm00002482,3-dihydroxy-3-methylbutanoateC5H10O4Chemical structure of 2,3-dihydroxy-3-methylbutanoate1756-18-9
Average134.1305Da
Monoisotopic134.0579088Da
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm00002593alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da
BASm00002603alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da

Displaying 1–10 of 4785 metabolites

Health Effects

Health ConditionRelationReference
Gi diseaseCausesPMC11149725
UtisCausesPMC11434687
Colorectal cancerCausesPMC12198655
Pyogenic liver abscessesCausesPMC12392612
UtiCausesPMC13014981
ColibacillosisCausesPMC13255289
Enteric infectionsCausesPMC13255289
Foodborne infectionsCausesPMC13255289
Clinical mastitisCausesPMC13293316
DiarrheaCausesPMC3035056

Displaying health effects 1 – 10 of 103 in total