Escherichia coli strain FWSEC0339

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Escherichia

Description

Escherichia coli strain FWSEC0339 is a Gram-negative, rod-shaped bacterium characterized as a facultative anaerobe. It is capable of both aerobic and anaerobic respiration, allowing it to thrive in various environments, particularly those associated with host organisms. This strain exhibits mobility due to the presence of flagella and typically arranges itself in pairs or as singles. The optimal growth temperature for FWSEC0339 is 37°C, placing it within the mesophilic range, which is conducive to its survival in warm-blooded hosts. It possesses a single replicon and two membranes, which are typical features of Gram-negative bacteria. Its biotic relationship is free-living, suggesting it can exist independently while being associated with a diverse range of hosts. FWSEC0339 has been implicated in a wide array of health issues, particularly in humans and other vertebrates, including urinary tract infections (UTIs), gastrointestinal infections, and even severe conditions like hemolytic uremic syndrome (HUS) and neonatal meningitis. The strain's ability to affect multiple hosts, including mammals such as Homo sapiens and Bos taurus, as well as various other vertebrates and invertebrates, underscores its ecological versatility. The extensive pathogenic effects associated with FWSEC0339 highlight its role in public health and veterinary medicine, emphasizing the need for continued surveillance and research into its transmission and virulence mechanisms. Understanding its interactions with different hosts can provide insights into its ecological dynamics and the potential for zoonotic transfer.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusEscherichia
SpeciesEscherichia coli
Strainstrain FWSEC0339

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Escherichia coli strain FWSEC0339
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Bos taurus
Cell arrangementPairs - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Escherichia coli strain FWSEC0339 plasmid unnamed1

Gene Summary

Adenine Count

1207656 bp

Thymine Count

1210951 bp

Guanine Count

1239828 bp

Cytosine Count

1254687 bp

Genome Length

4919637 bp

Protein-coding Genes

4426 genes

Non-Coding Genes

343 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
glutathione abc transporter substrate-binding protein gsibC9115_13845Not AvailablePositive2815298 - 281683656420.0
glutathione abc transporter permeaseC9115_13850Not AvailablePositive2816854 - 281777434068.5
glutathione abc transporter permeaseC9115_13855Not AvailablePositive2817777 - 281868833254.3
eal domain-containing proteinC9115_13860Not AvailablePositive2818866 - 282121490048.7
ggdef domain-containing proteinC9115_13865Not AvailablePositive2821222 - 282255049923.8
30s ribosomal protein s12 methylthiotransferase rimoC9115_13870Not AvailableNegative2822597 - 282392249584.6
biofilm regulator bssrC9115_13875Not AvailablePositive2824135 - 282451814536.6
pqq-dependent sugar dehydrogenaseC9115_13880Not AvailablePositive2824629 - 282574441086.8
glutathione s-transferaseC9115_13885Not AvailableNegative2825741 - 282636723714.4
d-alanyl-d-alanine carboxypeptidaseC9115_13890Not AvailablePositive2826613 - 282781543643.4

Displaying genes 2811 – 2820 of 4796 in total

Metabolites

4790 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000173(R)-3-Hydroxybutyric acidC4H8O3Chemical structure of (R)-3-Hydroxybutyric acid625-72-3
Average104.0473Da
Monoisotopic104.047344122Da
BASm0000217alpha-ribazoleC14H18N2O4Chemical structure of alpha-ribazoleNot available
Average278.3037Da
Monoisotopic278.126657074Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm0000238(R)-3-phenyllactateC9H9O3Chemical structure of (R)-3-phenyllactateNot available
Average165.169Da
Monoisotopic165.05571773Da
BASm00002482,3-dihydroxy-3-methylbutanoateC5H10O4Chemical structure of 2,3-dihydroxy-3-methylbutanoate1756-18-9
Average134.1305Da
Monoisotopic134.0579088Da
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm00002593alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da
BASm00002603alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da

Displaying 1–10 of 4790 metabolites

Health Effects

Health ConditionRelationReference
Gi diseaseCausesPMC11149725
UtisCausesPMC11434687
Colorectal cancerCausesPMC12198655
Pyogenic liver abscessesCausesPMC12392612
UtiCausesPMC13014981
ColibacillosisCausesPMC13255289
Enteric infectionsCausesPMC13255289
Foodborne infectionsCausesPMC13255289
Clinical mastitisCausesPMC13293316
DiarrheaCausesPMC3035056

Displaying health effects 1 – 10 of 103 in total