Escherichia coli strain FWSEC0298

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Escherichia

Description

Escherichia coli strain FWSEC0298 is a Gram-negative, rod-shaped bacterium that exhibits mobility and possesses flagella. It is classified as a facultative anaerobe, allowing it to thrive in both aerobic and anaerobic environments. The strain is mesophilic, with an optimal growth temperature of 37°C, typical for many pathogenic E. coli strains. FWSEC0298 is associated with a wide range of hosts, including Homo sapiens (humans), Gallus gallus (chickens), various mammals including Bos taurus (cattle), Sus scrofa (pigs), and others, as well as certain plant species like Solanum lycopersicum (tomato) and Brassica oleracea var. italica (broccoli). This diverse host range highlights its adaptability and ecological significance. The strain is known to be free-living and is associated with numerous health effects in humans, particularly urinary tract infections (UTIs), gastrointestinal infections, and other serious conditions such as septicemia and neonatal meningitis. These pathogenic effects underscore the strain's potential impact on public health, particularly in foodborne infections and clinical settings. Given the strain's ability to infect both humans and various animal species, it is evident that FWSEC0298 plays a significant role in the microbiome of its hosts and can contribute to disease transmission across species. Its wide-ranging pathogenic effects remind us of the importance of monitoring E. coli strains in both clinical and agricultural contexts to mitigate health risks associated with infections.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusEscherichia
SpeciesEscherichia coli
Strainstrain FWSEC0298

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Escherichia coli strain FWSEC0298
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Bos taurus
Cell arrangementPairs - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Escherichia coli strain FWSEC0298 plasmid unnamed6

Gene Summary

Adenine Count

1311236 bp

Thymine Count

1315804 bp

Guanine Count

1317367 bp

Cytosine Count

1346325 bp

Genome Length

5300977 bp

Protein-coding Genes

4915 genes

Non-Coding Genes

318 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
duf3302 domain-containing proteinC9085_12810Not AvailablePositive2664868 - 266519112404.2
hlyd family secretion proteinC9085_12815Not AvailablePositive2665197 - 266633341744.6
lysr family transcriptional regulatorC9085_12820Not AvailableNegative2666330 - 266730437276.5
mipa/ompv family proteinC9085_12825Not AvailablePositive2667428 - 266816827383.9
l-ribulose-5-phosphate 4-epimeraseC9085_12835Not AvailableNegative2668515 - 266921025620.3
l-ribulose-5-phosphate 3-epimeraseC9085_12840Not AvailableNegative2669204 - 267006432513.0
3-keto-l-gulonate-6-phosphate decarboxylase uladC9085_12845Not AvailableNegative2670057 - 267071923562.2
carbohydrate kinaseC9085_12850Not AvailableNegative2670716 - 267221255305.2
trap transporter substrate-binding proteinC9085_12855Not AvailableNegative2672216 - 267320235989.1
2,3-diketo-l-gulonate trap transporter permeaseC9085_12860Not AvailableNegative2673215 - 267449245371.0

Displaying genes 2761 – 2770 of 5263 in total

Metabolites

4785 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000173(R)-3-Hydroxybutyric acidC4H8O3Chemical structure of (R)-3-Hydroxybutyric acid625-72-3
Average104.0473Da
Monoisotopic104.047344122Da
BASm0000217alpha-ribazoleC14H18N2O4Chemical structure of alpha-ribazoleNot available
Average278.3037Da
Monoisotopic278.126657074Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm0000238(R)-3-phenyllactateC9H9O3Chemical structure of (R)-3-phenyllactateNot available
Average165.169Da
Monoisotopic165.05571773Da
BASm00002482,3-dihydroxy-3-methylbutanoateC5H10O4Chemical structure of 2,3-dihydroxy-3-methylbutanoate1756-18-9
Average134.1305Da
Monoisotopic134.0579088Da
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm00002593alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da
BASm00002603alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da

Displaying 1–10 of 4785 metabolites

Health Effects

Health ConditionRelationReference
Gi diseaseCausesPMC11149725
UtisCausesPMC11434687
Colorectal cancerCausesPMC12198655
Pyogenic liver abscessesCausesPMC12392612
UtiCausesPMC13014981
ColibacillosisCausesPMC13255289
Enteric infectionsCausesPMC13255289
Foodborne infectionsCausesPMC13255289
Clinical mastitisCausesPMC13293316
DiarrheaCausesPMC3035056

Displaying health effects 1 – 10 of 103 in total