Escherichia coli strain FWSEC0289

Escherichia coli strain FWSEC0289 is a gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic lifestyle. It is capable of mobility due to the presence of flagella and typically arranges itself in pairs or as singles. This strain is mesophilic, with an optimal growth temperature of 37°C, and possesses a single replicon and two membranes. FWSEC0289 is predominantly host-associated, demonstrating a free-living biotic relationship. It has been identified in a wide range of hosts, including Homo sapiens, various livestock species such as Gallus gallus (chickens) and Bos taurus (cattle), as well as several other animals and plants, including Solanum lycopersicum (tomatoes) and Apis mellifera (honeybees). This diversity in host range suggests that FWSEC0289 may play a significant role in the microbiomes of these organisms, potentially influencing their health and disease states. Clinically, this strain is associated with multiple health effects in humans, including urinary tract infections (UTIs), gastrointestinal infections, and severe conditions such as neonatal meningitis and hemolytic uremic syndrome (HUS). The presence of FWSEC0289 in both healthy and diseased hosts highlights its potential impact on public health and animal health, where it can contribute to a variety of infections and disease processes. Understanding the ecological roles and pathogenic mechanisms of strains like FWSEC0289 is crucial for developing strategies to mitigate their health impacts in both human and veterinary medicine.