Escherichia coli strain FWSEC0263

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Escherichia

Description

Escherichia coli strain FWSEC0263 is a Gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic metabolism. This strain is characterized by its mobility, facilitated by the presence of flagella, and it typically exists in pairs or as singles. With an optimal growth temperature of 37°C, FWSEC0263 falls within the mesophilic temperature range. The strain is notably host-associated, demonstrating a diverse range of biotic relationships and infecting numerous hosts, including Homo sapiens (humans), Gallus gallus (chickens), Bos taurus (cattle), and various other mammals, birds, and plants. This versatility highlights its ecological adaptability across multiple environments and hosts. FWSEC0263 is associated with a wide array of health effects, particularly in humans. It is implicated in conditions such as urinary tract infections (UTIs), gastrointestinal infections, neonatal meningitis, septicemia, and various forms of diarrhea, including hemorrhagic colitis and hemolytic uremic syndrome (HUS). The extensive list of associated health issues underscores the pathogenicity of this strain in human health. The presence of a single replicon and a double membrane structure is typical of E. coli and supports its classification within the Enterobacteriaceae family. Given its ability to cause significant health challenges across different hosts and its adaptability to various environments, FWSEC0263 serves as a pertinent example of the complexities of microbial interactions within ecosystems and their potential impacts on both human and animal health. Understanding the behaviors and pathogenic potential of such strains is crucial for developing effective prevention and treatment strategies.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusEscherichia
SpeciesEscherichia coli
Strainstrain FWSEC0263

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Escherichia coli strain FWSEC0263
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Bos taurus
Cell arrangementPairs - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Escherichia coli strain FWSEC0263 plasmid unnamed4

Gene Summary

Adenine Count

1244940 bp

Thymine Count

1238201 bp

Guanine Count

1272978 bp

Cytosine Count

1271322 bp

Genome Length

5032686 bp

Protein-coding Genes

4512 genes

Non-Coding Genes

311 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
[fe-s]-dependent transcriptional repressor feocC9050_14135Not AvailablePositive2942175 - 29424118688.72
recombination-promoting nuclease rpnaC9050_14140Not AvailablePositive2942614 - 294350733920.0
pimeloyl-acp methyl ester esterase biohC9050_14145Not AvailableNegative2943727 - 294449728601.8
dna utilization protein gntxC9050_14150Not AvailablePositive2944535 - 294521825707.8
fe-s biogenesis protein nfuaC9050_14155Not AvailablePositive2945277 - 294585220998.9
gluconate transporterC9050_14160Not AvailablePositive2946213 - 294752945969.6
4-alpha-glucanotransferaseC9050_14165Not AvailableNegative2947577 - 294965878467.5
maltodextrin phosphorylaseC9050_14170Not AvailableNegative2949668 - 295206190513.3
hth-type transcriptional regulator maltC9050_14175Not AvailablePositive2952684 - 2955389103066.0
rna 3'-terminal phosphate cyclaseC9050_14180Not AvailableNegative2955432 - 295644835952.6

Displaying genes 3001 – 3010 of 4823 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

4785 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000173(R)-3-Hydroxybutyric acidC4H8O3Chemical structure of (R)-3-Hydroxybutyric acid625-72-3
Average104.0473Da
Monoisotopic104.047344122Da
BASm0000217alpha-ribazoleC14H18N2O4Chemical structure of alpha-ribazoleNot available
Average278.3037Da
Monoisotopic278.126657074Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm0000238(R)-3-phenyllactateC9H9O3Chemical structure of (R)-3-phenyllactateNot available
Average165.169Da
Monoisotopic165.05571773Da
BASm00002482,3-dihydroxy-3-methylbutanoateC5H10O4Chemical structure of 2,3-dihydroxy-3-methylbutanoate1756-18-9
Average134.1305Da
Monoisotopic134.0579088Da
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm00002593alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da
BASm00002603alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da

Displaying 1–10 of 4785 metabolites

Health Effects

Health ConditionRelationReference
Gi diseaseCausesPMC11149725
UtisCausesPMC11434687
Colorectal cancerCausesPMC12198655
Pyogenic liver abscessesCausesPMC12392612
UtiCausesPMC13014981
ColibacillosisCausesPMC13255289
Enteric infectionsCausesPMC13255289
Foodborne infectionsCausesPMC13255289
Clinical mastitisCausesPMC13293316
DiarrheaCausesPMC3035056

Displaying health effects 1 – 10 of 103 in total