Escherichia coli strain FWSEC0262

Escherichia coli strain FWSEC0262 is a Gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic metabolism and is motile due to the presence of flagella. It is associated with a variety of hosts, including Homo sapiens, Gallus gallus, and Bos taurus, among others, indicating its versatility in colonizing different biological niches. This strain thrives optimally at 37°C, which aligns with its mesophilic classification. FWSEC0262 is notable for its association with multiple health effects in humans, primarily linked to urinary tract infections (UTIs) and gastrointestinal diseases. It is implicated in conditions such as peritonitis, neonatal meningitis, and various forms of diarrheal disease, including hemorrhagic colitis and hemolytic uremic syndrome (HUS). The strain's diverse pathogenicity highlights its ability to cause serious health issues, particularly in vulnerable populations such as neonates. Additionally, FWSEC0262's free-living biotic relationship and its ability to infect a wide range of hosts, including mammals, birds, and certain invertebrates, suggest an ecological flexibility that allows it to thrive in varied environments. The strain's presence in agricultural and natural settings underscores its potential as a pathogen in both human health and animal husbandry. In summary, E. coli strain FWSEC0262 serves as an important model for studying pathogenicity and host interactions due to its diverse health impacts and adaptability to various hosts. Understanding its biology and ecology can inform strategies for managing infections and preventing disease transmission.