Escherichia coli strain FWSEC0258

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Escherichia

Description

Escherichia coli strain FWSEC0258 is a Gram-negative, rod-shaped bacterium that is facultatively anaerobic and exhibits mobility due to the presence of flagella. This strain is categorized as mesophilic, with an optimal growth temperature of 37°C. It has a single replicon and features a double membrane structure, common to the Enterobacteriaceae family. FWSEC0258 is primarily host-associated, indicating its association with various organisms, including Homo sapiens (humans) and several domesticated and wild animals, such as Gallus gallus (chickens), Bos taurus (cattle), and Canis lupus familiaris (dogs). It also associates with a variety of plants and invertebrates, reflecting its versatility in different ecological niches. This strain is known to be pathogenic to humans, contributing to a wide range of health effects. It is implicated in urinary tract infections (UTIs), gastrointestinal infections, and severe conditions such as neonatal meningitis and hemolytic uremic syndrome (HUS). The diverse array of diseases associated with FWSEC0258 underscores its potential as a significant public health concern, particularly in foodborne infections and complications arising from its pathogenicity. The ecological insight from the data suggests that E. coli strain FWSEC0258's ability to inhabit multiple hosts, including various animal species and plants, enhances its transmission potential and survival in diverse environments. This broad host range likely contributes to its persistence in ecological systems and its role as a significant pathogen in both human and veterinary medicine.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusEscherichia
SpeciesEscherichia coli
Strainstrain FWSEC0258

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Escherichia coli strain FWSEC0258
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Bos taurus
Cell arrangementPairs - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Escherichia coli strain FWSEC0258 plasmid unnamed5

Gene Summary

Adenine Count

1267740 bp

Thymine Count

1265046 bp

Guanine Count

1276314 bp

Cytosine Count

1296850 bp

Genome Length

5116614 bp

Protein-coding Genes

4751 genes

Non-Coding Genes

234 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
acid stress chaperone hdeaC9045_19045Not AvailableNegative3903921 - 390425311858.2
protein hdedC9045_19050Not AvailablePositive3904508 - 390508020904.6
acid resistance transcriptional activator gadeC9045_19055Not AvailablePositive3905879 - 390640620600.6
hypothetical proteinC9045_19060Not AvailableNegative3906407 - 39066859789.79
multidrug resistance protein mdteC9045_19065Not AvailablePositive3906745 - 390790241193.0
multidrug efflux rnd transporter permease subunitC9045_19070Not AvailablePositive3907927 - 3911040111555.0
acid resistance transcriptional activator gadwC9045_19075Not AvailableNegative3911403 - 391213128025.0
dna-binding transcriptional regulator gadxC9045_19080Not AvailableNegative3912499 - 391332331436.2
hypothetical proteinC9045_19085Not AvailablePositive3913779 - 3921259276427.0
hypothetical proteinC9045_19095Not AvailablePositive3921618 - 39218248123.14

Displaying genes 3781 – 3790 of 4995 in total

Metabolites

4785 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000173(R)-3-Hydroxybutyric acidC4H8O3Chemical structure of (R)-3-Hydroxybutyric acid625-72-3
Average104.0473Da
Monoisotopic104.047344122Da
BASm0000217alpha-ribazoleC14H18N2O4Chemical structure of alpha-ribazoleNot available
Average278.3037Da
Monoisotopic278.126657074Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm0000238(R)-3-phenyllactateC9H9O3Chemical structure of (R)-3-phenyllactateNot available
Average165.169Da
Monoisotopic165.05571773Da
BASm00002482,3-dihydroxy-3-methylbutanoateC5H10O4Chemical structure of 2,3-dihydroxy-3-methylbutanoate1756-18-9
Average134.1305Da
Monoisotopic134.0579088Da
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm00002593alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da
BASm00002603alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da

Displaying 1–10 of 4785 metabolites

Health Effects

Health ConditionRelationReference
Gi diseaseCausesPMC11149725
UtisCausesPMC11434687
Colorectal cancerCausesPMC12198655
Pyogenic liver abscessesCausesPMC12392612
UtiCausesPMC13014981
ColibacillosisCausesPMC13255289
Enteric infectionsCausesPMC13255289
Foodborne infectionsCausesPMC13255289
Clinical mastitisCausesPMC13293316
DiarrheaCausesPMC3035056

Displaying health effects 1 – 10 of 103 in total