Escherichia coli strain FWSEC0252

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Escherichia

Description

Escherichia coli strain FWSEC0252 is a gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic lifestyle. It is capable of movement due to the presence of flagella and typically arranges in pairs or as singles. The optimal growth temperature for FWSEC0252 is 37°C, classifying it as mesophilic, and it has a single replicon with a characteristic double membrane structure. This strain is primarily host-associated and has been identified in a wide range of hosts, including Homo sapiens (humans), Gallus gallus (chickens), Bos taurus (cattle), and various other vertebrates and invertebrates. This extensive host range indicates its adaptability and ecological versatility. FWSEC0252 is known to be pathogenic to humans, associated with several health conditions, including urinary tract infections (UTIs), gastrointestinal infections, neonatal meningitis, and more severe complications such as hemolytic uremic syndrome (HUS) and septicemia. The presence of this strain in multiple hosts, including domesticated animals and wildlife, underscores its potential as a zoonotic pathogen and its relevance in food safety, as it can lead to foodborne infections. The ecological insight here is that E. coli FWSEC0252 exemplifies the complex interactions between bacteria, their hosts, and the environment, highlighting the importance of monitoring such strains in both clinical and agricultural settings. Understanding its pathogenicity and host relationships can aid in developing strategies to mitigate its health impacts.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusEscherichia
SpeciesEscherichia coli
Strainstrain FWSEC0252

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Escherichia coli strain FWSEC0252
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Bos taurus
Cell arrangementPairs - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Escherichia coli strain FWSEC0252


Gene Summary

Adenine Count

1317068 bp

Thymine Count

1316618 bp

Guanine Count

1339280 bp

Cytosine Count

1339174 bp

Genome Length

5322755 bp

Protein-coding Genes

4726 genes

Non-Coding Genes

562 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
bcr/cfla family multidrug efflux mfs transporterC9039_00645Not AvailablePositive146442 - 14763243341.4
hypothetical proteinC9039_00650Not AvailablePositive147965 - 14830912525.9
microcin c abc transporter atp-binding protein yejfC9039_00655Not AvailableNegative148313 - 14990258699.8
abc transporter permeaseC9039_00660Not AvailableNegative149904 - 15092938094.6
abc transporter permeaseC9039_00665Not AvailableNegative150929 - 15202340376.7
abc transporter substrate-binding proteinC9039_00670Not AvailableNegative152024 - 15383869713.6
cyclic di-gmp phosphodiesteraseC9039_00675Not AvailableNegative153920 - 15547658531.4
bifunctional murein dd-endopeptidase/murein ld-carboxypeptidaseC9039_00680Not AvailableNegative155657 - 15622321041.1
lipid a 1-diphosphate synthaseC9039_00685Not AvailableNegative156635 - 15734826792.8
gtp-binding proteinC9039_00690Not AvailableNegative157387 - 15837336085.3

Displaying genes 741 – 750 of 5290 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

4785 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000173(R)-3-Hydroxybutyric acidC4H8O3Chemical structure of (R)-3-Hydroxybutyric acid625-72-3
Average104.0473Da
Monoisotopic104.047344122Da
BASm0000217alpha-ribazoleC14H18N2O4Chemical structure of alpha-ribazoleNot available
Average278.3037Da
Monoisotopic278.126657074Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm0000238(R)-3-phenyllactateC9H9O3Chemical structure of (R)-3-phenyllactateNot available
Average165.169Da
Monoisotopic165.05571773Da
BASm00002482,3-dihydroxy-3-methylbutanoateC5H10O4Chemical structure of 2,3-dihydroxy-3-methylbutanoate1756-18-9
Average134.1305Da
Monoisotopic134.0579088Da
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm00002593alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da
BASm00002603alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da

Displaying 1–10 of 4785 metabolites

Health Effects

Health ConditionRelationReference
Gi diseaseCausesPMC11149725
UtisCausesPMC11434687
Colorectal cancerCausesPMC12198655
Pyogenic liver abscessesCausesPMC12392612
UtiCausesPMC13014981
ColibacillosisCausesPMC13255289
Enteric infectionsCausesPMC13255289
Foodborne infectionsCausesPMC13255289
Clinical mastitisCausesPMC13293316
DiarrheaCausesPMC3035056

Displaying health effects 1 – 10 of 103 in total