Escherichia coli strain FWSEC0246

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Escherichia

Description

Escherichia coli strain FWSEC0246 is a Gram-negative, rod-shaped bacterium characterized by its facultative anaerobic metabolism and the presence of flagella, which facilitates its mobility. This strain is notable for its ability to thrive in host-associated habitats, primarily within a wide range of hosts, including Homo sapiens, Gallus gallus, Bos taurus, and many others across various taxa such as Metazoa and Vertebrata. FWSEC0246 is mesophilic, with an optimal growth temperature of 37°C, making it well-suited for growth within warm-blooded hosts. FWSEC0246 exhibits a diverse array of pathogenic effects, being implicated in numerous health conditions such as urinary tract infections (UTIs), gastrointestinal infections, and neonatal meningitis. The strain has been associated with severe outcomes, including hemorrhagic colitis and hemolytic uremic syndrome (HUS), underscoring its potential as a significant human pathogen. The wide array of diseases caused by this strain highlights its adaptability and pathogenicity across different biological systems. As a free-living organism, FWSEC0246 has developed associations with both animal and plant hosts, indicating its ecological versatility. The presence of this strain in various environments and its role in health complications present an important consideration for understanding the dynamics of microbial communities and their impacts on host health. The implications of its pathogenicity and its capacity to inhabit diverse hosts reflect the intricate relationships between microorganisms and their environments, emphasizing the need for continued research on bacterial interactions and their effects on human health.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusEscherichia
SpeciesEscherichia coli
Strainstrain FWSEC0246

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Escherichia coli strain FWSEC0246
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Bos taurus
Cell arrangementPairs - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Escherichia coli strain FWSEC0246 plasmid unnamed2

Gene Summary

Adenine Count

1320033 bp

Thymine Count

1316773 bp

Guanine Count

1337505 bp

Cytosine Count

1344313 bp

Genome Length

5328574 bp

Protein-coding Genes

4668 genes

Non-Coding Genes

643 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
ribosome hibernation promoting factorC9033_07370Not AvailableNegative1539108 - 153939510750.9
rna polymerase factor sigma-54C9033_07375Not AvailableNegative1539418 - 154085154054.9
lipopolysaccharide abc transporter atp-binding proteinC9033_07380Not AvailableNegative1540899 - 154162426802.3
lipopolysaccharide abc transporter substrate-binding protein lptaC9033_07385Not AvailableNegative1541631 - 154218820128.1
lps export abc transporter periplasmic protein lptcC9033_07390Not AvailableNegative1542157 - 154273221703.8
3-deoxy-d-manno-octulosonate 8-phosphate phosphatase kdscC9033_07395Not AvailableNegative1542729 - 154329520016.3
arabinose 5-phosphate isomerase kdsdC9033_07400Not AvailableNegative1543316 - 154430235198.3
calcium/sodium antiporterC9033_07405Not AvailableNegative1544316 - 154529334756.9
phospholipid abc transporter atp-binding protein mlafC9033_07410Not AvailablePositive1545503 - 154631229098.6
phospholipid abc transporter permeaseC9033_07415Not AvailablePositive1546320 - 154710227865.0

Displaying genes 2071 – 2080 of 5314 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

4785 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000173(R)-3-Hydroxybutyric acidC4H8O3Chemical structure of (R)-3-Hydroxybutyric acid625-72-3
Average104.0473Da
Monoisotopic104.047344122Da
BASm0000217alpha-ribazoleC14H18N2O4Chemical structure of alpha-ribazoleNot available
Average278.3037Da
Monoisotopic278.126657074Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm0000238(R)-3-phenyllactateC9H9O3Chemical structure of (R)-3-phenyllactateNot available
Average165.169Da
Monoisotopic165.05571773Da
BASm00002482,3-dihydroxy-3-methylbutanoateC5H10O4Chemical structure of 2,3-dihydroxy-3-methylbutanoate1756-18-9
Average134.1305Da
Monoisotopic134.0579088Da
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm00002593alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da
BASm00002603alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da

Displaying 1–10 of 4785 metabolites

Health Effects

Health ConditionRelationReference
Gi diseaseCausesPMC11149725
UtisCausesPMC11434687
Colorectal cancerCausesPMC12198655
Pyogenic liver abscessesCausesPMC12392612
UtiCausesPMC13014981
ColibacillosisCausesPMC13255289
Enteric infectionsCausesPMC13255289
Foodborne infectionsCausesPMC13255289
Clinical mastitisCausesPMC13293316
DiarrheaCausesPMC3035056

Displaying health effects 1 – 10 of 103 in total