Escherichia coli strain FWSEC0154

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Escherichia

Description

Escherichia coli strain FWSEC0154 is a Gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic lifestyle. This strain is known to be motile and possesses flagella, allowing it to move through its host-associated habitat. It thrives optimally at 37°C, within a mesophilic temperature range, and is characterized by having a single replicon and two membranes. FWSEC0154 has a broad spectrum of hosts, including Homo sapiens, various livestock (such as Gallus gallus and Bos taurus), other mammals, and even some plants like Solanum lycopersicum and Brassica oleracea var. italica. This diverse host range highlights the strain's adaptability and potential ecological significance. Health effects associated with E. coli FWSEC0154 are significant, as it is implicated in numerous medical conditions, including urinary tract infections (UTIs), gastrointestinal infections, neonatal meningitis, and septicemia. The strain is also linked to severe outcomes such as hemolytic uremic syndrome (HUS), which can lead to renal failure and anemia. Its role in foodborne infections and diarrheal diseases further emphasizes the public health impact of this strain. In summary, the pathogenic potential of E. coli strain FWSEC0154, particularly in humans, underlines its importance in both clinical settings and ecological contexts. The bacterium’s ability to inhabit a wide variety of hosts suggests it plays a significant role in host-microbe interactions, influencing health outcomes across multiple species.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusEscherichia
SpeciesEscherichia coli
Strainstrain FWSEC0154

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Escherichia coli strain FWSEC0154
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Bos taurus
Cell arrangementPairs - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Escherichia coli strain FWSEC0154 plasmid unnamed4

Gene Summary

Adenine Count

1291565 bp

Thymine Count

1298986 bp

Guanine Count

1319805 bp

Cytosine Count

1310270 bp

Genome Length

5232938 bp

Protein-coding Genes

4882 genes

Non-Coding Genes

218 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
intimin type epsilonC9004_18535Not AvailablePositive3835456 - 3838302103316.0
type iii secretion system lee inner membrane ring protein escdC9004_18540Not AvailableNegative3838682 - 383990245226.7
tyea family type iii secretion system gatekeeper subunitC9004_18545Not AvailablePositive3840045 - 384110039977.9
secretion protein espaC9004_18550Not AvailablePositive3841158 - 384173620505.1
secretion protein espdC9004_18555Not AvailablePositive3841749 - 384289139578.9
eaebC9004_18560Not AvailablePositive3842912 - 384385633221.8
type iii secretion system lee chaperone cesd2C9004_18565Not AvailablePositive3843863 - 384427015762.7
type iii secretion system lee needle major subunit escfC9004_18570Not AvailablePositive3844307 - 38445288127.69
escg/yscg/ssah family type iii secretion system needle protein co-chaperoneC9004_18575Not AvailablePositive3844534 - 384481210437.7
hypothetical proteinC9004_18580Not AvailablePositive3845028 - 384577125318.9

Displaying genes 3691 – 3700 of 5105 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

4785 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000173(R)-3-Hydroxybutyric acidC4H8O3Chemical structure of (R)-3-Hydroxybutyric acid625-72-3
Average104.0473Da
Monoisotopic104.047344122Da
BASm0000217alpha-ribazoleC14H18N2O4Chemical structure of alpha-ribazoleNot available
Average278.3037Da
Monoisotopic278.126657074Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm0000238(R)-3-phenyllactateC9H9O3Chemical structure of (R)-3-phenyllactateNot available
Average165.169Da
Monoisotopic165.05571773Da
BASm00002482,3-dihydroxy-3-methylbutanoateC5H10O4Chemical structure of 2,3-dihydroxy-3-methylbutanoate1756-18-9
Average134.1305Da
Monoisotopic134.0579088Da
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm00002593alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da
BASm00002603alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da

Displaying 1–10 of 4785 metabolites

Health Effects

Health ConditionRelationReference
Gi diseaseCausesPMC11149725
UtisCausesPMC11434687
Colorectal cancerCausesPMC12198655
Pyogenic liver abscessesCausesPMC12392612
UtiCausesPMC13014981
ColibacillosisCausesPMC13255289
Enteric infectionsCausesPMC13255289
Foodborne infectionsCausesPMC13255289
Clinical mastitisCausesPMC13293316
DiarrheaCausesPMC3035056

Displaying health effects 1 – 10 of 103 in total