Escherichia coli strain FWSEC0133

Escherichia coli strain FWSEC0133 is a Gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic metabolism, allowing it to thrive in both aerobic and anaerobic environments. This strain is motile and possesses flagella, contributing to its mobility. It is mesophilic, with an optimal growth temperature of 37°C, which aligns with the average body temperature of many hosts, suggesting an adaptation to host-associated environments. FWSEC0133 has a diverse range of hosts, including various mammals such as Homo sapiens, Bos taurus, and Canis lupus familiaris, as well as avian species like Gallus gallus and even invertebrates like Acanthamoeba. This wide host range highlights its ecological versatility and ability to persist in different biological niches. Health effects associated with FWSEC0133 include a variety of serious conditions, primarily affecting the urinary tract, gastrointestinal system, and potentially leading to systemic infections. It has been implicated in urinary tract infections (UTIs), peritonitis, gastrointestinal infections, and neonatal meningitis, among others. The strain's pathogenicity is particularly noted in humans, where it can cause severe outcomes such as hemolytic uremic syndrome (HUS) and renal failure. The presence of FWSEC0133 in multiple hosts suggests a complex biotic relationship, where it may act as a commensal organism in some species while being pathogenic in others. This duality underscores the significance of understanding microbial interactions within host ecosystems, particularly in the context of disease emergence and public health.